Sarah Harden

No ORCID on file · 4 papers in corpus · active 2022-2025

Study types

  • preprint 2
  • article 1
  • other 1

Condition tags

  • endometriosis 4
  • infertility 2
article 2025
Beyond one-size-fits-all: single-cell transcriptomic signatures predict drug efficacy and reveal responder subgroups in endometriosis
·doi:10.64898/2025.12.09.693218

Abstract Endometriosis affects ∼10% of reproductive-age women, yet targeted non-hormonal therapies remain unavailable, and treatment response is highly variable. Here, we apply a single-cell framework to resolve therapeutic heterogeneity at…

preprint 2025
Whole genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis
Communications medicine ·doi:10.1038/s43856-026-01641-3

BACKGROUND: Endometriosis, despite its high prevalence, is underdiagnosed and poorly managed due to lack of clinically validated biomarkers and pathophysiological insight. Menstrual blood-derived stem cells have been implicated in disease p…

other 2023
Peritoneal autoantibody profiling identifies p53 as an autoantibody target in endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2023.02.025

OBJECTIVE: To map the peritoneal autoantibody (AAb) landscape in women with endometriosis. DESIGN: Case-control laboratory study. SETTING: Academic medical and research units. PATIENT(S): Women who presented with or without endometriosis…

preprint 2022
Peritoneal autoantibody landscape in endometriosis
·doi:10.1101/2022.05.27.493373

ABSTRACT Women with endometriosis have a profound association with autoimmunity. An excess of autoantigens in the peritoneal cavity resulting from retrograde menstruation could lead to inflammation and pathologic autoimmunity. Using a nativ…