Endometriosis is a common cause of chronic pelvic pain and infertility. It is defined as the occurrence of endometrial tissue outside the uterine cavity and can manifest as a peritoneal, ovarian or infiltrating form, the latter being referr…
OBJECTIVE: To study the function of miR-145, known to be dysregulated in endometriosis, and to identify its target genes in an in vitro endometriosis model. DESIGN: Experimental laboratory study. SETTING: University medical centers. PATI…
microRNAs are small non-coding RNAs which regulate gene expression at the posttranscriptional and translational level. microRNAs have previously been demonstrated to be dysregulated in endometriosis, a hormone-dependent disease associated w…
ObjectiveTo study the function of syndecan-1 (SDC1) and its potential regulator miR-10b in endometriosis.DesignExperimental laboratory study.SettingUniversity medical center.Patient(s)Not applicable.Intervention(s)The human endometriotic ce…