Harris RA

No ORCID on file · 3 papers in corpus · active 2005-2018
2018
Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques.
Genes & cancer ·doi:10.18632/genesandcancer.170

Colorectal cancer accounts for a substantial number of deaths each year worldwide. Lynch Syndrome is a genetic form of colorectal cancer (CRC) caused by inherited mutations in DNA mismatch repair (MMR) genes. Although researchers have devel…

2012
Early origins of adult disease: approaches for investigating the programmable epigenome in humans, nonhuman primates, and rodents.
ILAR journal ·doi:10.1093/ilar.53.3-4.306

According to the developmental origins of health and disease hypothesis, in utero experiences reprogram an individual for immediate adaptation to gestational perturbations, with the sequelae of later-in-life risk of metabolic disease. An al…

2005
Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol.
Behavioural brain research ·doi:10.1016/j.bbr.2005.06.026

Microarray analysis of human alcoholic brain and cultured cells exposed to ethanol showed significant changes in expression of genes related to immune or inflammatory responses, including chemokines and chemokine receptors. To test the hypo…