Hernandez L

No ORCID on file · 5 papers in corpus · active 2016-2023

Study types

  • other 2
  • preprint 1

Condition tags

  • endometriosis 3
  • infertility 1
  • endometrioma 1
  • die_deep_infiltrating 1
other 2023
Nature genetics ·doi:10.1038/s41588-022-01254-1

Endometriosis is a common condition in women that causes chronic pain and infertility and is associated with an elevated risk of ovarian cancer. We profiled transcriptomes of >370,000 individual cells from endometriomas (n = 8), endometrios…

2023
Cancers ·doi:10.3390/cancers15041315

The overexpression of inhibitor of apoptosis (IAP) proteins is strongly related to poor survival of women with ovarian cancer. Recurrent ovarian cancers resist apoptosis due to the dysregulation of IAP proteins. Mechanistically, Second Mito…

preprint 2021
·doi:10.1101/2021.05.20.445037

Abstract Endometriosis is a common, benign condition characterized by extensive heterogeneity in lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual cells from endometriomata (n=7), extra-ovarian endomet…

other 2021
Cell reports ·doi:10.1016/j.celrep.2021.108978

The human fallopian tube harbors the cell of origin for the majority of high-grade serous "ovarian" cancers (HGSCs), but its cellular composition, particularly the epithelial component, is poorly characterized. We perform single-cell transc…

2016
Gynecologic Oncology ·doi:10.1016/j.ygyno.2016.05.028

ObjectiveThe value of cell lines for pre-clinical work lies in choosing those with similar characteristics. Selection of cell lines is typically based on patient history, histological subtype at diagnosis, mutation patterns, or signaling pa…