Angiogenesis plays a critical role in the progression of endometriosis, with enhanced glycolysis accelerating pathological angiogenesis. Prior research has identified a central role for N6-methyladenosine (m6A) modification in regulating gl…
BACKGROUND: Hepatocellular carcinoma (HCC) mainly develops in cases of fibrosis and cirrhosis and is accompanied by intestinal flora disorder. HCC also affects CD8+ T cell immune function. 5,7-Dimethoxyflavone (DMF), an active flavonoid wit…
Abdominal pregnancy is a special type of ectopic pregnancy that require careful evaluation for accurate diagnosis and appropriate management. Detailed clinical presentations, surgical procedures, and histopathological examinations of five c…
OBJECTIVE: Our study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs). METHODS: The study population was sourced from two indepe…
INTRODUCTION: Chronic endometritis (CE) is regarded as a potential factor contributing to infertility and embryo implantation failure. The cause of CE remains unclear at present, but it might be associated with intrauterine microbial infect…
The issues of uncontrolled global population growth and unintended pregnancies are severe, and the existing contraceptive methods have numerous limitations, making the development of novel contraceptive technologies urgent. Contraceptive va…
INTRODUCTION: Alpha-linolenic acid (ALA), an essential polyunsaturated fatty acid, modulates gastrointestinal microbiota and host immunity, yet its regulatory mechanisms in dairy cows remain unclear. METHODS: This study investigated how di…
PURPOSE: To compare the effects of the gonadotrophin-releasing hormone (GnRH) agonist protocol, GnRH antagonist protocol, progestin-primed ovarian stimulation (PPOS) protocol, and mild stimulation/natural cycle protocol on the cumulative li…
OBJECTIVE: Special attention has been paid to genetic mechanisms that might have a significant impact on the context of the risk of developing endometriosis, in recent years. The study aimed to analyze the expression levels of three inflamm…
INTRODUCTION AND HYPOTHESIS: Female bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome (IC/BPS). Numerous research indirectly prove that Female bladder pain syndrome (FBPS) is associated with immun…
OBJECTIVE: To identify if there is a high-risk group for chronic endometritis (CE) in infertile women. METHODS: A retrospective single-center cohort study was conducted on 209 infertile women with CE and 843 women without. Both univariate …
Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…
Endometriosis is marked by the ectopic growth, spread, and invasion of endometrial tissue beyond the uterus, resulting in recurrent bleeding, pain, reproductive challenges, and the formation of nodules or masses. Despite advancements in det…
PURPOSE: To investigate the dynamic changes of serum Anti-Müllerian Hormone (AMH) and Inhibin B (INHB) during controlled ovarian hyperstimulation (COH) in patients with polycystic ovarian syndrome (PCOS) and analyze their correlation with C…
PURPOSE: Preoperative diagnosis of uterine leiomyosarcoma (ULMS) can be difficult due to its ability to mimic benign leiomyomas (LM). The current study aimed to investigate the influence of preoperative clinical characteristics and hematolo…
PURPOSE: The International Federation of Gynecology and Obstetric (FIGO) stage is critical to guiding the treatments of ovarian cancer (OC). We tried to develop a model to predict the FIGO stage of OC through machine learning algorithms wit…
PURPOSE: To explore the impact of seasonal variations on the risks of hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) in women who undergo in vitro fertilization (IVF) treatment. METHODS: We retrospectivel…
BACKGROUND: Visceral fat accumulation and dyslipidaemia are associated with infertility symptoms. The cardiometabolic index (CMI) is a comprehensive quantitative measure of central obesity and dyslipidaemia. However, the link between the fe…
BACKGROUND: The C-reactive protein-triglyceride glucose index (CTI) is a promising new marker for evaluating the severity of inflammation. Endometriosis (EM) is a prevalent chronic inflammatory condition influenced by estrogen, primarily af…
BACKGROUND: Infertility in women of reproductive age is a major worldwide health problem. Oxidative stress, inflammatory responses, and dysregulation of lipid metabolism are among the factors that contribute to female infertility. The ratio…
BACKGROUND: While anti-Müllerian hormone (AMH) serves as a well-established biomarker of ovarian reserve, its association with early miscarriage risk remains inconsistently characterized across previous research. To address this evidence ga…
OBJECTIVE: To explore the role of endometrial defects in the pathogenesis of abnormal uterine bleeding (AUB). DESIGN: Retrospective case-control study. SETTING: Two tertiary centres. POPULATION OR SAMPLE: We included 155 patients with ca…
This article reports the clinical diagnosis and treatment of a 42-year-old female patient with a giant cervical leiomyoma, a rare condition. A review of the literature over the past 30 years reveals only one reported case of a cervical inte…
INTRODUCTION: Low-grade endometrial stromal sarcoma (LGESS) is a rare malignant tumor of the uterus, characterized by slow growth. Early-stage LGESS is associated with favorable survival, but it has a high recurrence rate. The primary treat…