Tao H

No ORCID on file · 8 papers in corpus · active 2012-2026

Study types

  • other 2
  • preprint 1

Condition tags

  • endometriosis 3
other 2026
A preliminary single-cell map of endometriosis suggests roles for fibroblast metabolism and macrophage polarization in disease progression
Functional & integrative genomics ·doi:10.1007/s10142-026-01860-w

Single-cell RNA sequencing (scRNA-seq) serves as a crucial tool for rapidly and accurately quantifying tissue heterogeneity and its associated biological significance within highly organized life systems. In this study, we utilized scRNA-se…

preprint 2025
Alterations in the uterine microbiome drive the progression of endometriosis via neutrophil-mediated AKT-mTOR signaling pathway.
·doi:10.21203/rs.3.rs-8183082/v1

Abstract Background The microbiome of the female reproductive system has been extensively studied; however, the correlation between uterine microbial alterations and endometriosis remains unclear. Methods Endometrial and lesion tissues wer…

other 2024
Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis
Frontiers in bioscience (Landmark edition) ·doi:10.31083/j.fbl2912421

BACKGROUND: Endometriosis is a complicated and enigmatic disease that significantly diminishes the quality of life for women affected by this condition. Increased levels of human telomerase reverse transcriptase (TERT) mRNA and telomerase a…

2024
What are the barriers and facilitators to help-seeking behaviour for symptoms in patients with ovarian cancer in China? A qualitative study.
BMJ open ·doi:10.1136/bmjopen-2024-087602

ObjectivesTo explore the barriers and facilitators to help-seeking behaviour for symptoms among patients with ovarian cancer in China.DesignThis semistructured interview-based study used a descriptive phenomenological research method.Settin…

2021
G protein-coupled receptors: structure- and function-based drug discovery.
Signal transduction and targeted therapy ·doi:10.1038/s41392-020-00435-w

As one of the most successful therapeutic target families, G protein-coupled receptors (GPCRs) have experienced a transformation from random ligand screening to knowledge-driven drug design. We are eye-witnessing tremendous progresses made …

2021
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Nature communications ·doi:10.1038/s41467-021-23827-0

Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-cont…

2017
Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway.
Journal of bone oncology ·doi:10.1016/j.jbo.2017.09.005

This study aimed to investigate the effects of Estrogen receptor β (ERβ) on osteosarcoma cells, and explore the regulatory mechanisms involved in this process. Osteosarcoma U2-OS cells consisted four groups, and treated by E2, E2 + LY294002…

2012
MicroRNAs up-regulated by CagA of Helicobacter pylori induce intestinal metaplasia of gastric epithelial cells.
PloS one ·doi:10.1371/journal.pone.0035147

CagA of Helicobacter pylori is a bacterium-derived oncogenic protein closely associated with the development of gastric cancers. MicroRNAs (miRNAs) are a class of widespread non-coding RNAs, many of which are involved in cell growth, cell d…