Po‐Han Lin — Endo Lab

article 2020

The effects of isoliquiritigenin on endometriosis in vivo and in vitro study

Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2020.153214

BackgroundEndometriosis is a common gynaecological disease characterized by growth of uterine endometrial tissue, outside the uterine cavity, on the ovaries, oviduct and pelvic peritoneum. Isoliquiritigenin (ISL) is a natural flavonoid isol…

article 2020

The Inhibitory Effect of Extra Virgin Olive Oil and Its Active Compound Oleocanthal on Prostaglandin-Induced Uterine Hypercontraction and Pain—Ex Vivo and In Vivo Study

Nutrients ·doi:10.3390/nu12103012

Primary dysmenorrhea is a common occurrence in adolescent women and is a type of chronic inflammation. Dysmenorrhea is due to an increase in oxidative stress, which increases cyclooxygenase-2 (COX-2) expression, increases the concentration …

article 2019

Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation

·doi:10.3390/cancers11081131

Uterine leiomyomas, also known as fibroids, are common and prevalent in women of reproductive age. In this study, the effect of Isoliquiritigenin (ISL), a licorice flavonoid, on the anti-proliferation of uterine leiomyoma was investigated. …

article 2019

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

·doi:10.1111/jpi.12620

The circadian nature of melatonin has a protective effect on the progression of female reproductive cancers, including breast and ovarian cancers. However, the effect of melatonin on the growth of uterine leiomyoma is still unclear. In this…