Zhang G

Endometriosis is a common gynecological disorder characterized by chronic pelvic pain, infertility, and systemic symptoms, with currently limited treatment options. Amygdalin, a cyanogenic glycoside derived from bitter apricot kernels, has …

BACKGROUND: High-intensity focused ultrasound (HIFU), a noninvasive treatment method, has attracted increasing attention in recent years for the management of gynaecological diseases. This review summarizes current literature on the applica…

This study aimed to develop and validate a clinical prediction model for the success of the focused ultrasound ablation system (FUAS) in treating adenomyosis. A retrospective analysis was conducted on 250 patients from Qingdao Women and Chi…

BACKGROUND: Studies have shown that dysregulation of the gut microbiota (GM) plays a crucial role in the development of endometriosis (EMs). Study aimed to investigate the potential of protective GM metabolites in treating EM through networ…

BACKGROUND: N6-methyladenosine (m6A) modification regulates the processes of RNA splicing, subcellular localization, translation and stability by changing the RNA structure and the interaction between RNA and RNA-binding proteins to ensure …

BACKGROUND: Sexual health plays a crucial role in the overall health and quality of life of adults. Currently, various Patient-Reported Outcome Measures (PROMs) exist globally to assess sexual health from different dimensions. However, the …

Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…

BackgroundThe risk of preterm birth (PTB) is associated with maternal hyperglycemia but differs by combinations of abnormal oral glucose tolerance test (OGTT) values. However, the potential pathway by which maternal hyperglycemia affects PT…

BACKGROUND: Endometrial hepatoid adenocarcinoma (HAC) is an exceedingly rare tumor. Histologically, the tumor is predominantly characterized by HAC with additional components, as documented in previous reports. The coexistence of endometria…

AimThis study aimed to compare the diagnostic accuracy of ultrasound (US) and magnetic resonance imaging (MRI) in the detection of placenta accreta spectrum (PAS) disorders in a single tertiary care setting.Materials and methodsAll eligible…

[This corrects the article DOI: 10.3389/fimmu.2023.1115504.].

BACKGROUND: Rectal endometriosis is a complex condition requiring multidisciplinary treatment. Accurate preoperative assessment is critical for selecting the appropriate surgical technique, with transvaginal ultrasound (TVS) and endorectal …

This study analyzes 324 captive giant panda breeding events (1998-2023) to unravel maternal and gestational drivers of cub survival and health-the largest dataset of its kind to date. Key variables included gestational duration, maternal ag…

BackgroundPolycystic ovary syndrome (PCOS) has been extensively studied as a common female endocrine disease. In recent years, the relationship between circadian rhythm and PCOS has gradually drawn attention, although the precise nature of …

The extracellular matrix (ECM) is essential for tissue homeostasis, ensuring structural stability, facilitating cell-cell communication, and tightly controlling key cellular processes, including proliferation, differentiation, and migration…

Chengcheng Ren,1,* Yanan He,1,* Yunlong Zhao,2 Guangmei Zhang1 1Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China; 2Plastic Surgery Laser Center, T…

BACKGROUND: Endometriosis (EMs) is a benign gynecological disorder that exhibits several malignant characteristics, including proliferation and angiogenesis. N6-methyladenosine (m6A) modification plays a crucial role in regulating RNA splic…

PurposeDifferentiating between benign and malignant ovarian masses remains a significant clinical challenge. Although the Ovarian-Adnexal Reporting and Data System Ultrasound Version 2022 (O-RADS US v2022) provides standardized terminology …

Sheep (Ovis aries) are valuable biomedical models for studying human reproductive biology, however, the transcriptional dynamics underlying their ovarian development remain insufficiently characterized. In this study, we profiled 61,649 sin…

Endometriosis (EMs) is a common gynecological disorder. According to the most widely recognized theory of retrograde menstruation, endometrial cells require completion of three key steps during ectopic implantation: adhesion, invasion, and …

INTRODUCTION: Endometriosis is a common chronic gynecological condition that affects approximately 10% of women of reproductive age worldwide. METHODS: This study utilized large-scale genome-wide association study data and explored the cau…

High intensity focused ultrasound (HIFU) is an effective and safe non-invasive treatment method, widely used in the treatment of uterine fibroids and adenomyosis in the field of gynecology. The side effects in HIFU is low in incidence and m…

Endometriosis (EM) is a chronic inflammatory disease that is one of the most common causes of gynecological systemic lesions in women before menopause. The most representative histological feature of EM is that the endometrium appears outsi…

BACKGROUND: Low-grade chronic inflammation is observed in women with polycystic ovary syndrome (PCOS). A recent genome-wide association study (GWAS) suggested that several inflammation marker levels were altered in the blood routine tests i…