Yutaka Osuga

ORCID: 0000-0002-6660-1066 · 302 papers in corpus
nonrandomized-trial 2017
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13406

AIM: We aimed to investigate the safety and efficacy of dienogest (DNG), a progestational 19-norsteroid, administered for 52 weeks in patients with symptomatic adenomyosis. METHODS: A total of 130 patients with adenomyosis received 2 mg of…

other 2017
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.09.036

OBJECTIVES: To characterize peritoneal dendritic cells (DCs) in endometriosis and to clarify their role in its etiology. DESIGN: Experimental. SETTING: University hospital. PATIENT(S): Sixty-three women (35 patients with endometriosis an…

2017
2017
observational 2017
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13198

AIM: Our objective was to determine the preoperative factors associated with difficulty in total laparoscopic hysterectomy (TLH). METHODS: This retrospective clinical study included 157 patients who underwent TLH for leiomyoma or adenomyos…

2017
·doi:10.1530/endoabs.49.gp134

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

2017
2017
2017
2017
·doi:10.1016/j.jri.2017.10.025
2017
lab-animal 2016
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12592

OBJECTIVE: We investigated α-7 nAchR expression in human peritoneal macrophages and examined whether activation of nAchR might be a new therapy for endometriosis. MATERIALS AND METHODS: Human peritoneal fluid mononuclear cells (PFMC) were …

observational 2016
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-016-0209-2

BACKGROUND: Endometriosis has been shown to be associated with second- to third-trimester pregnancy complications such as preterm birth and placenta previa, but the evidence is inconsistent. We hypothesized that endometriosis severity might…

2016
observational 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.07.1077

OBJECTIVE: To determine the prevalence rate of subsequent development of ovarian cancer after excision of endometrioma. DESIGN: Retrospective cross-sectional study. SETTING: University hospital. PATIENT(S): A total of 485 women with endo…

2016
·doi:10.1016/j.jri.2016.04.016
2016
·doi:10.1016/j.jri.2016.04.184
other 2016
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2016.10.053

OBJECTIVES: To evaluate the in vivo effect of dienogest on proliferation, apoptosis, aromatase expression, vascular density, nerve growth factor (NGF) expression and nerve fiber density in human adenomyosis tissue. STUDY DESIGN: Twelve wom…

lab-animal 2016
Journal of Reproductive Immunology ·doi:10.1016/j.jri.2016.12.002

Drospirenone has been used as a progestin in oral contraceptives with ethinyl estradiol (DRSP/EE) and is expected to regulate endometriosis, however, the direct effects of drospirenone on endometriosis have not been clarified. The aim of th…

lab-animal 2016
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1515

CONTEXT: Endometriosis is an estrogen-dependent, chronic inflammatory disease. Recent studies have shown that vitamin D (VD) is an effective modulator of the immune system and plays an important role in controlling many inflammatory disease…

2016
·doi:10.1016/j.jri.2016.04.241
2016
·doi:10.1016/j.jri.2016.04.073
2016
2016
2016