Melnyk N

No ORCID on file · 5 papers in corpus · active 2010-2014

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 3
other 2014
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2013.107

Ovarian endometrioid carcinomas and endometrial endometrioid carcinomas share many histological and molecular alterations. These similarities are likely due to a common endometrial epithelial precursor cell of origin, with most ovarian endo…

2013
The Journal of Pathology ·doi:10.1002/path.4230

High-grade serous ovarian cancer (HGSC) is characterized by poor outcome, often attributed to the emergence of treatment-resistant subclones. We sought to measure the degree of genomic diversity within primary, untreated HGSCs to examine th…

2013
PloS one ·doi:10.1371/journal.pone.0072162

BackgroundOVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis …

other 2011
The American journal of surgical pathology ·doi:10.1097/PAS.0b013e3182262743

Translocations resulting in gene fusion are characteristic of endometrial stromal tumors (ESTs). Rearrangements of JAZF1, SUZ12, PHF1, and EPC1 have been reported in endometrial stromal nodules (ESNs), endometrial stromal sarcomas (ESSs), a…

article 2010
The New England journal of medicine ·doi:10.1056/nejmoa1008433

BACKGROUND: Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described. METHODS: We sequenced the whole transcriptomes of 18 ovarian clear-ce…