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- endometriosis 4
- infertility 1
- endometrioma 1
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Dienogest (DNG) is a therapeutic medication used in endometriosis treatment. Limited data are available regarding its mechanism of action on endometrial cells. Using in vivo and in vitro models, we investigated whether DNG treatment causes …
Both environmental and genetic factors interact and play a critical role in the pathogenesis of endometriosis. We analyzed the plasma levels of 12 polychlorinated biphenyl (PCB) congeners with genetic polymorphisms of glutathione-S-transfer…
Endometriosis is a chronic inflammatory disease that affects 10% to 15% of all women of reproductive age. Several studies show an association between endometriosis and infertility; however, clear causality remains unproven. The association …
Mammalian target of rapamycin (mTOR) is known to be a major negative regulator of autophagy. Recent studies have shown that mTOR activity is abnormally increased in endometriotic lesions. In endometriosis, abnormal mTOR activity may contrib…