Tong Li

No ORCID on file · 10 papers in corpus · active 2010-2024

Study types

  • article 6
  • other 2
  • preprint 1

Condition tags

  • endometriosis 8
  • dysmenorrhea 1
  • infertility 1
  • endometrioma 1
  • adenomyosis 1
article 2024
Dissecting the cell microenvironment of ovarian endometrioma through single-cell RNA sequencing
Science China. Life sciences ·doi:10.1007/s11427-024-2638-9

Ovarian endometrioma (OE), also known as "chocolate cysts," is a cystic mass that develops in the ovaries due to endometriosis and is a common gynecological condition characterized by the growth of endometrial tissue outside the uterus, lea…

2023
Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19
·doi:10.1101/2023.12.20.572494
other 2023
Multi-Body Biomarker Entrapment System: An All-Encompassing Tool for Ultrasensitive Disease Diagnosis and Epidemic Screening
Advanced materials (Deerfield Beach, Fla.) ·doi:10.1002/adma.202304119

Ultrasensitive identification of biomarkers in biofluids is essential for the precise diagnosis of diseases. For the gold standard approaches, polymerase chain reaction and enzyme-linked immunosorbent assay, cumbersome operational steps hin…

preprint 2021
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
·doi:10.1101/2021.01.02.425073

Abstract The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout the menstrual cycle in response to ovarian hormones. We have generated single-cell and spatial reference maps of the human uterus and 3D endome…

article 2021
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
Nature genetics ·doi:10.1038/s41588-021-00972-2

The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout the menstrual cycle in response to ovarian hormones. We have generated dense single-cell and spatial reference maps of the human uterus and three-dimens…

article 2014
Identification of differentially methylated genes in the malignant transformation of ovarian endometriosis
Journal of ovarian research ·doi:10.1186/1757-2215-7-73

BACKGROUND: Key roles for epigenetic mechanisms in tumorigenesis are well accepted, while the relationship between gene methylation and malignant transformation of ovarian endometriosis (EMS) was seldom reported. In this study, we aimed to …

other 2012
DNA hypomethylation of the COX-2 gene promoter is associated with up-regulation of its mRNA expression in eutopic endometrium of endometriosis
European journal of medical research ·doi:10.1186/2047-783X-17-12

BACKGROUND: Accumulated evidence reveals that cyclooxygenase-2 (COX-2) was overexpressed in eutopic endometrium of endometriosis, which may play a critical role in the pathogenesis of endometriosis. However, few studies have been performed …

article 2012
Expression of Th1 and Th2 cytokine-associated transcription factors, T-bet and GATA-3, in the eutopic endometrium of women with endometriosis
Acta histochemica ·doi:10.1016/j.acthis.2012.01.005
article 2011
[Epigenetic inactivation of SPOCK2 in the malignant transformation of ovarian endometriosis].
Zhonghua fu chan ke za zhi

OBJECTIVE: To investigate epigenetic inactivation of SPOCK2 gene in the malignant transformation of ovarian endometriosis (EM) by comparing the methylation status and protein expression of SPOCK2 gene in the malignant tissues, ectopic endom…

article 2010
MRI Diagnosis of uterine adenomyosis

Objective To study the MRI features and its diagnostic value of uterine adenomyosis.Methods MRI features of 26 cases of uterine adenomyosis proved by surgery and pathology were reviewed and correlated with manifestations.Results MRI and pat…