The majority of research within reproductive and gynecologic health, or investigating ART, is observational in design. One of the most critical challenges for observational studies is confounding, while one of the most important for discove…
A mediator is a factor that occurs after the exposure of interest, precedes the outcome of interest (i.e. between the exposure and the outcome) and is associated with both the exposure and the outcome of interest (i.e. is on the pathway bet…
ObjectiveTo determine whether younger oocyte donor age is associated with better outcomes after in vitro fertilization (IVF) compared with older oocyte donor age.DesignA retrospective cohort study.SettingLarge academically affiliated infert…
ObjectivesTo evaluate the association of fresh and frozen embryo transfer with the development of ischemic placental disease (IPD), hypothesizing that differences in implantation environment affect placentation and thus pregnancy outcomes.D…
Study questionDoes inverse probability weighting (IPW) provide a more valid estimate of the cumulative incidence of live birth after multiple cycles of IVF?Summary answerIPW can provide a more accurate estimate of treatment success for coun…
OBJECTIVE: To determine the prevalence of occult pre-malignant or malignant uterine pathology at the time of laparoscopic surgery with open power morcellation for benign gynecologic disease. METHODS: The present multicenter, retrospective c…
PurposeThis retrospective cohort study aimed to determine whether age influences treatment discontinuation among insured patients undergoing in vitro fertilization (IVF). We hypothesized that the youngest patients would be the least likely …
ObjectiveThe objective of this study was to determine the effect of alcohol consumption on outcomes among women undergoing in vitro fertilization (IVF).DesignThis study is a retrospective cohort study.SettingThis study was performed in a pr…
BackgroundIt is unknown whether certain factors are associated with the success of in vitro fertilization (IVF) in women with inflammatory bowel disease (IBD).AimThis study assessed whether certain characteristics are associated with greate…
PurposeThe aim of this study is to evaluate the outcomes of in vitro fertilization (IVF), including cumulative live birth rate, among women <25 years, 25 to <30 years, and 30 to <35 years.MethodsA retrospective cohort study of all women 18 …
Background & aimsInflammatory bowel disease (IBD) affects women of reproductive age, so there are concerns about its effects on fertility. We investigated the success of in vitro fertilization (IVF) in patients with IBD compared with the ge…
ObjectiveWe sought to determine whether the success of intrauterine insemination (IUI) varies based on the type of health care provider performing the procedure.Study designThis was a retrospective cohort study set at an infertility clinic …