Orazov MR

A trend toward comorbid conditions is seen in around 50% of gynecological patients, with a significant contribution made by endometriosis as a common and incurable gynecological condition. Over the last decades, the global burdens of differ…

Lyudmila M Mikhaleva,1 Victor E Radzinsky,2 Mekan R Orazov,2 Tatyana N Khovanskaya,1 Anastasia V Sorokina,1 Sergey A Mikhalev,3 Snezhana V Volkova,2 Victoria B Shustova,1 Mikhail Y Sinelnikov1 1Laboratory of Clinical Morphology, Research In…

OBJECTIVE: To review the mechanisms of endometriosis development, including those related to epigenetic mutations, cellular dysregulation, inflammatory processes, and oxidative stress. METHODS: A systematic literature review regarding curre…

There is a statistically significant difference in the frequency of implantation in the group of patients with endometriosis associated with infertility compared with the control group. This has been confirmed by a number of different studi…

OBJECTIVE: To compare the effectiveness of two different treatment regimens of dydrogesterone in the management of endometriosis-related chronic pelvic pain. DESIGN: Observational, prospective cohort study over six months. SETTING: Twenty g…

Methods. For morphological studies it were using fragments of walls 60 uterus, received after hysterectomy in patients with pelvic pain on a background of diffuse adenomyosis II-III degree, and 30 uterus of women with painless form of adeno…

Objective. To study features of histamine metabolism in patients with chronic pelvic pain associated with external genital endometriosis. Methods. For quantitative assessment of histamine level in peripheral blood was taken from 100 patient…

Objective: to analyze the role of inflammatory and immune reactivity in the development of adenomyosis and its associated pain. Methods. For morphological studies it were using fragments of walls of 56 uterus received after hysterectomy in …