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N6-methyladenosine (m6A) is a critical regulator of female reproductive physiology, yet existing reviews have focused predominantly on oocytes. The objective of this review is to systematically evaluate the regulatory effects of m6A through…

BACKGROUND: Adenomyosis (AM) is a common benign gynecological disease, defined by the presence of endometrial glands and stroma deep within the myometrium, which is associated with hypertrophy and hyperplasia of the adjacent myometrium. It …

PURPOSE: To investigate the dynamic changes of serum Anti-Müllerian Hormone (AMH) and Inhibin B (INHB) during controlled ovarian hyperstimulation (COH) in patients with polycystic ovarian syndrome (PCOS) and analyze their correlation with C…

OBJECTIVE: The aim of this study was to investigate the emotional experience of patients with thin endometrium (TE) who have repeatedly cancelled their cycles due to unsuitability for embryo implantation during the endometrial preparation p…

BACKGROUND: Previous studies have focused on the effects of ambient air pollutant levels on assisted reproduction. This research focused on the combined effects of lower concentrations of air pollutants and multiple environmental factors on…

Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases of infertili…

OBJECTIVE: Clear cell borderline ovarian tumor is a rare subtype of borderline ovarian tumor for which the clinicopathological characteristics, management, and prognosis remain unclear. Herein, we describe the clinical features, treatment o…

[This corrects the article DOI: 10.3389/fimmu.2023.1115504.].

[This corrects the article DOI: 10.3389/fimmu.2021.641206.].

Bone remodeling represents a dynamic equilibrium orchestrated by mechanobiological and endocrine signals, with YAP/TAZ and ERα emerging as pivotal regulators of skeletal adaptation. YAP/TAZ functions as the central mechanotransduction hub o…

Ovarian cancer(OC) poses a significant clinical challenge due to its frequent peritoneal dissemination and development of chemotherapy resistance, contributing to poor patient outcomes. Chronic inflammation is a pivotal driver of disease in…

INTRODUCTION: To assess the effects of oral dydrogesterone on the recurrence rate of endometrial polyps (EPs) and abnormal uterine bleeding (AUB) symptoms after transcervical resection of polyps (TCRP). METHODS AND ANALYSIS: A randomised, …

OBJECTIVE: To investigate the effects of cold environment exposure on female reproductive capacity and explore its potential regulatory mechanisms. METHODS: Female mice were subjected to cold water immersion to simulate cold environment ex…

Female adnexal tumor of probable Wolffian origin (FATWO) is a rare gynecologic tumor. We describe a case of 53-year-old female patient in whom an adnexal mass was found. Microscopic examination revealed that the tumor arose in the adnexal s…

Infertility affects approximately 15% of couples at child-bearing ages and assisted reproductive technologies (ART), especially in vitro fertilization and embryo transfer (IVF-ET), provided infertile patients with an effective solution. The…

The increased risk of infertility and endometrial lesions (such as endometrial hyperplasia or cancer) in polycystic ovary syndrome (PCOS) are closely associated with the lack of cyclical transformation in the endometrium. However, the under…

BACKGROUND: Endometriosis (EMs) is a benign gynecological disorder that exhibits several malignant characteristics, including proliferation and angiogenesis. N6-methyladenosine (m6A) modification plays a crucial role in regulating RNA splic…

Chengcheng Ren,1,* Yanan He,1,* Yunlong Zhao,2 Guangmei Zhang1 1Department of Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China; 2Plastic Surgery Laser Center, T…

Endometriosis (EM) significantly impacts the quality of life, and its diagnosis currently relies on surgery, which carries risks and may miss early lesions. Noninvasive biomarkers are urgently needed for early diagnosis and personalized tre…

Pelvic organ prolapse (POP) significantly impacts patients' quality of life, and current treatment options remain limited due to high recurrence rates, making the exploration of new therapeutic targets essential. Using data from the FinnGen…

PURPOSE: To evaluate whether prior SARS-CoV-2 infection adversely affects live birth and perinatal outcomes following subsequent frozen-thawed embryo transfer (FET) and to further investigate whether the time interval between infection and …

Cuproptosis is a kind of programmed cell death in which copper reacts with the cycloaliphatic component of the tricarboxylic acid (TCA) cycle. In this study, we devised a predictive model and a theoretical framework to examine the variation…

INTRODUCTION: Minimally invasive techniques have been widely adopted for hysterectomy, including Transumbilical Laparoendoscopic Single-Site Surgery (TU-LESS) and Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES). Howeve…