William H. Wallace

ORCID: 0000-0001-8080-5674 · 3 papers in corpus · active 2009-2012

Study types

  • article 3
article 2012
Physiological sex steroid replacement in premature ovarian failure: randomized crossover trial of effect on uterine volume, endometrial thickness and blood flow, compared with a standard regimen
·doi:10.1093/humrep/des004

BACKGROUND: Premature ovarian failure (POF) is currently managed by non-physiological sex steroid regimens which are inadequate at optimizing uterine characteristics. Previous short-term studies have demonstrated some benefits of a sex ster…

article 2011
Physiological Versus Standard Sex Steroid Replacement in Young Women With Premature Ovarian Failure: Effects on Bone Mass Acquisition and Turnover
·doi:10.1097/ogx.0b013e31821a4aaa

It is well-recognized that young women with untreated premature ovarian failure (POF) are at increased risk of osteoporosis and bone fracture. Large, randomized trials have demonstrated that hormone replacement therapy with estrogen/progest…

article 2009
Cardiovascular Effects of Physiological and Standard Sex Steroid Replacement Regimens in Premature Ovarian Failure
·doi:10.1161/hypertensionaha.108.126516

Current hormone replacement therapy may not optimize cardiovascular health in women with premature ovarian failure. We compared the effects of physiological and standard sex steroid replacement regimens on cardiovascular health in these wom…