H. Thöle

ORCID: 0000-0002-7577-4129 · 2 papers in corpus

article 2007

A sensitive HPLC method for the assessment of metabolic conversion of estrogens

The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2007.03.006

Disorders of estrogen-responsive tissues are frequently associated with aberrations in steroid metabolism due to altered expression of synthesizing and metabolizing enzymes. For instance, overexposure to unopposed 17beta-estradiol has been …

article 2007

Estrogen metabolizing enzymes in endometrium and endometriosis

Human Reproduction ·doi:10.1093/humrep/dem310

BACKGROUND: Estradiol (E(2)) is an important promoter of the growth of both eutopic and ectopic endometrium. The findings with regard to the expression and activity of steroidogenic enzymes in endometrium of controls, in endometrium of endo…