Ge Chen

No ORCID on file · 4 papers in corpus · active 2017-2022

Study types

  • article 3

Condition tags

  • endometriosis 3
article 2022
A novel nude mouse model for studying the pathogenesis of endometriosis
Experimental and therapeutic medicine ·doi:10.3892/etm.2022.11425

Endometriosis is a common female gynecological disease that is characterized by the presence of functional endometrial tissue outside the uterine cavity. At present, many animal models have been established. However, previous studies consis…

article 2022
Whole-exome sequencing and functional validation reveal a rare missense variant in MMP7 that confers ovarian endometriosis risk
Human molecular genetics ·doi:10.1093/hmg/ddac062

Prior studies have shown that genetic factors play important roles in ovarian endometriosis. Herein, we first analyzed the whole-exome sequencing data from 158 patients with ovarian endometriosis and 385 local control women without endometr…

article 2021
Frequent DYSF rare variants/mutations in 152 Han Chinese samples with ovarian endometriosis
Archives of gynecology and obstetrics ·doi:10.1007/s00404-021-06094-8

PurposeEndometriosis is a common chronic gynecological disease greatly affecting women health. Prior studies have implicated that dysferlin (DYSF) aberration might be involved in the pathogenesis of ovarian endometriosis. In the present stu…

2017
DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers
·doi:10.1101/163204

DNA modifications such as 5-methylcytosines (5mC) and 5-hydroxymethylcytosines (5hmC) are epigenetic marks known to affect global gene expression in mammals( 1, 2 ). Given their prevalence in the human genome, close correlation with gene e…