Yuan F

ORCID: 0000-0002-5210-8510 · 12 papers in corpus
lab-animal 2026
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2607561123

Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality of lif…

observational 2025
Journal of clinical laboratory analysis ·doi:10.1002/jcla.25126

BACKGROUND: Breast cancer (BC) is an aggressive tumor. Circulating tumor cells (CTCs) are a potential biomarker for the prognosis of cancer patients. This study aimed to explore the prognostic significance of CTCs in patients with BC. METH…

case-report 2025
Frontiers in medicine ·doi:10.3389/fmed.2025.1634101

BACKGROUND: Alarelin acetate, a synthetic gonadotropin-releasing hormone (GnRH) analogue, is widely used to manage endometriosis and hormone-sensitive malignancies. Although its safety profile is generally favorable, we report the first doc…

other 2025
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03602-6

PURPOSE: This study aimed to explore the roles of spermatozoal sialidase NEU1 and NEU3 in affecting the fertilization rate of in vitro fertilization (IVF), and whether sperm sialidase NEU1 and NEU3 can be used as predictors of IVF outcome. …

meta-analysis 2025
BMC pregnancy and childbirth ·doi:10.1186/s12884-025-08271-y

OBJECTIVE: Intrauterine Adhesions (IUA), including Asherman's Syndrome, are a significant cause of female infertility, while stem cell interventions emerge as a promising therapeutic strategy. This meta-analysis aims to systematically evalu…

lab-animal 2024
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2322934121

EPH receptors (EPHs), the largest family of tyrosine kinases, phosphorylate downstream substrates upon binding of ephrin cell surface-associated ligands. In a large cohort of endometriotic lesions from individuals with endometriosis, we fou…

lab-animal 2024
Endocrinology ·doi:10.1210/endocr/bqae003

Endometriosis is a common and debilitating disease, affecting ∼170 million women worldwide. Affected patients have limited therapeutic options such as hormonal suppression or surgical excision of the lesions, though therapies are often not …

review 2022
Frontiers in pharmacology ·doi:10.3389/fphar.2022.965902

Cyperi Rhizoma (CR) is the dry rhizome of Cyperus rotundus L., a Cyperaceae plant. It has a long history of clinical medication and is known as the "holy medicine" of gynecology. CR smells sweet and bitter. It has the effect of soothing the…

observational 2019
International journal of clinical and experimental pathology

Uterine cervical cancer (UCC) causes more than one quarter of a million deaths per year in many developing countries. Nearly all cases of cervical cancer result from infection with the human papillomavirus. After high-risk HPV infection, mo…

observational 2016
BMC cancer ·doi:10.1186/s12885-016-2480-1

BACKGROUND: Occult invasive cervical cancer (OICC) is sometimes incidentally found in surgical specimens after a simple hysterectomy (SH). This study was aimed at identifying a subset of patients with OICC who have a favorable prognosis. Th…

lab-animal 2016
Endocrinology ·doi:10.1210/en.2016-1234

Polycystic ovary syndrome (PCOS) progression involves abnormal insulin signaling. SH2 domain-containing adaptor protein (Lnk) may be an important regulator of the insulin signaling pathway. We investigated whether Lnk was involved in insuli…

observational 2016
Gynecologic Oncology ·doi:10.1016/j.ygyno.2016.10.009

OBJECTIVES: To investigate the prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma (OCCC). METHODS: The medical records of patients with stage I OCCC who had undergone complete staging surgery followed b…