Grützmann R

No ORCID on file · 5 papers in corpus · active 2013-2024
2024
Paraduodenal pancreatitis as diagnostic challenge: clinical and morphological features of patients with pancreatic pathology involving the pancreatic groove.
Annals of gastroenterology ·doi:10.20524/aog.2024.0914

BackgroundParaduodenal pancreatitis (PP) is an inflammation involving the groove zone, delimited by the duodenum lumen, bile duct, and the head of the pancreas. This area may also be involved during acute pancreatitis (AP). The differential…

2022
The use of single-stapling techniques reduces anastomotic complications in minimal-invasive rectal surgery.
International journal of colorectal disease ·doi:10.1007/s00384-022-04197-5

BackgroundLeakage of rectal anastomoses is one of the most important and feared complications in colorectal surgery. Apart from patient-specific risk factors, technical aspects may influence the occurrence of anastomotic complications. This…

2019
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice.
Science (New York, N.Y.) ·doi:10.1126/science.aaw3145

Glycosylation alterations are indicative of tissue inflammation and neoplasia, but whether these alterations contribute to disease pathogenesis is largely unknown. To study the role of glycan changes in pancreatic disease, we inducibly expr…

2015
Blood Glucose Homeostasis in the Course of Partial Pancreatectomy--Evidence for Surgically Reversible Diabetes Induced by Cholestasis.
PloS one ·doi:10.1371/journal.pone.0134140

Background and aimPartial pancreatic resection is accompanied not only by a reduction in the islet cell mass but also by a variety of other factors that are likely to interfere with glucose metabolism. The aim of this work was to characteri…

2013
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
Nature genetics ·doi:10.1038/ng.2730

Chronic pancreatitis is an inflammatory disorder of the pancreas. We analyzed CPA1, encoding carboxypeptidase A1, in subjects with nonalcoholic chronic pancreatitis (cases) and controls in a German discovery set and three replication sets. …