Y-H. Chen

ORCID: 0009-0009-5542-0460 · 8 papers in corpus · active 2018-2024

Study types

  • article 7
  • preprint 1

Condition tags

  • endometriosis 2
  • dysmenorrhea 1
  • mesh:D004715 1
article 2024
Regulatory roles of NAMPT and NAD+ metabolism in uterine leiomyoma progression: Implications for ECM accumulation, stemness, and microenvironment
·doi:10.1016/j.redox.2024.103411

Uterine leiomyoma (UL), commonly referred to as benign tumors, is characterized by excessive cell proliferation, extracellular matrix (ECM) accumulation, and the presence of stem cell-like properties. Nicotinamide adenine dinucleotide (NAD …

preprint 2024
Strategic Suppression of Nicotinamide Phosphoribosyl Transferase for Uterine Leiomyoma Progression Modulation
·doi:10.2139/ssrn.4845152
article 2020
The effects of isoliquiritigenin on endometriosis in vivo and in vitro study
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2020.153214
article 2020
The Inhibitory Effect of Extra Virgin Olive Oil and Its Active Compound Oleocanthal on Prostaglandin-Induced Uterine Hypercontraction and Pain—Ex Vivo and In Vivo Study
·doi:10.3390/nu12103012

Primary dysmenorrhea is a common occurrence in adolescent women and is a type of chronic inflammation. Dysmenorrhea is due to an increase in oxidative stress, which increases cyclooxygenase-2 (COX-2) expression, increases the concentration …

article 2020
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study
Biomedicines ·doi:10.3390/biomedicines8110528

Endometriosis is common in reproductive-age women and its pathology is to increase proliferation and migration to enhance epithelial-to-mesenchymal transition progression (EMT). However, treatments are currently limited, so it is important …

article 2019
Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation
·doi:10.3390/cancers11081131

Uterine leiomyomas, also known as fibroids, are common and prevalent in women of reproductive age. In this study, the effect of Isoliquiritigenin (ISL), a licorice flavonoid, on the anti-proliferation of uterine leiomyoma was investigated. …

article 2019
Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation
·doi:10.1111/jpi.12620

The circadian nature of melatonin has a protective effect on the progression of female reproductive cancers, including breast and ovarian cancers. However, the effect of melatonin on the growth of uterine leiomyoma is still unclear. In this…

article 2018
Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression
·doi:10.1159/000493660

BACKGROUND/AIMS: Uterine leiomyomas (ULs) are benign uterine tumors, and the most notable pathophysiologic feature of ULs is excessive accumulation of extracellular matrix (ECM). Fucoidan is a polysaccharide extracted from brown seaweeds th…