Charles W. Drescher

other 2025

Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube

Nature communications ·doi:10.1038/s41467-025-58145-2

The human Fallopian tube (FT) is an important organ in the female reproductive system and has been implicated as a site of origin for pelvic serous cancers, including high-grade serous tubo-ovarian carcinoma (HGSC). We have generated compre…

diagnostic-accuracy 2011

Potential role of HE4 in multimodal screening for epithelial ovarian cancer

Journal of the National Cancer Institute ·doi:10.1093/jnci/djr359

In screening for epithelial ovarian cancer, unnecessary surgery can be reduced by limiting use of transvaginal ultrasound (TVU) to women with increasing CA125 serum levels. Replacing or augmenting TVU with measurement of a serum marker spec…

case-report 2006

Clear cell adenocarcinoma of the vagina in a patient with vaginal endometriosis

Gynecologic Oncology ·doi:10.1016/j.ygyno.2006.06.044

BACKGROUND: Malignant transformation of endometriosis is an infrequent complication of endometriosis. Extragonadal disease is uncommon. CASE: 55-year-old female presented with postmenopausal bleeding. Physical examination revealed a 2-cm p…