Purpose This review focuses on the use of the gonadotropin-releasing hormone (GnRH) agonists, a typically marginalized class of drugs, and describes their role in the management of endometriosis, with special interest in 4 regions: Western …
The molecular biological features of the eutopic and ectopic endometrium were studied in 46 patients with adenomyosis, 44 with endometrioid cysts in the ovaries, and 34 with disseminated mixed forms of genital endometriosis. Reproductive-ag…
In a group of patients with endometriosis and in a control group of healthy women, the polymorphism of the following systems were studied: ABO and RH blood-group systems; serum proteins haptoglobin (HP), transferrin (TF), vitamin D-transpor…
A total of 100 patients with disseminated forms of external genital endometriosis were administered multiple-modality treatment including surgery and antihormone therapy. Twenty patients with the same diagnosis were controls and subjected t…
Tumor markers CA 125, CA 19-9, and carcinoembryonic antigen (CEA) were measured in the blood sera of 396 inpatients of different age. In 139 patients the measurements were carried out over time. Hoffman La Roche enzyme immunoassay test kits…
The total number of patients with severe forms of endometriosis treated in our department for the past 18 years is 1904. The treatment included surgery by laparotomy, laparoscopy and/or vaginal access, followed by hormonal therapy with dana…
CA-125 antigen was assayed in 108 patients with the most prevalent gynecologic diseases by enzyme immunoassay. Its blood levels were found to be under 35 U/ml in the patients with inflammatory diseases. In endometriosis and benign ovarian t…