Kenneth P. Winnard

article 2007

Endometriosis-induced vaginal hyperalgesia in the rat: Effect of estropause, ovariectomy, and estradiol replacement

Pain ·doi:10.1016/j.pain.2007.09.022

Endometriosis (ENDO) is a painful disorder defined by extrauteral endometrial growths. It is created in rats by autotransplanting pieces of uterus (which form cysts), or, for shamENDO, fat (no cysts). ENDO induces vaginal hyperalgesia, like…

article 2006

Cross-organ interactions between reproductive, gastrointestinal, and urinary tracts: modulation by estrous stage and involvement of the hypogastric nerve

·doi:10.1152/ajpregu.00455.2006

Central nervous system neurons process information converging from the uterus, colon, and bladder, partly via the hypogastric nerve. This processing is influenced by the estrous cycle, suggesting the existence of an estrous-modifiable centr…

article 2006

Opposing viscerovisceral effects of surgically induced endometriosis and a control abdominal surgery on the rat bladder

Fertility and sterility ·doi:10.1016/j.fertnstert.2006.03.026

ObjectiveTo determine, in rats, how surgically induced endometriosis and a control surgery (partial hysterectomy; sutures in abdomen) affects micturition thresholds and bladder vascular permeability.DesignTwo animal studies, each performed …