Signorini S

No ORCID on file · 4 papers in corpus · active 2008-2021

Condition tags

  • infertility 1
2021
Dioxin exposure associated with fecundability and infertility in mothers and daughters of Seveso, Italy.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa324

Study questionIs there an association between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and fecundability and infertility among Seveso women and their daughters?Summary answerTCDD exposure is associated with a decrease in fecundab…

2018
AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study.
International journal of epidemiology ·doi:10.1093/ije/dyy165

Background2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is proposed to interfere with fetal growth via altered activity of the aryl hydrocarbon receptor (protein: AHR; gene: AHR) pathway which regulates diverse biological and developmental …

2018
The Seveso accident: A look at 40 years of health research and beyond.
Environment international ·doi:10.1016/j.envint.2018.08.051

A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a known human carcinogen and potent endocrine disruptor. It is highly lipophilic and h…

2008
Dioxin exposure, from infancy through puberty, produces endocrine disruption and affects human semen quality.
Environmental health perspectives ·doi:10.1289/ehp.10399

BackgroundEnvironmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In 1976 an accident exposed residents in Seveso, Italy, to 2,3,7,8-tetrachlorodibenzo-p-…