Xiaohong Yan

ORCID: 0009-0001-4559-9059 · 4 papers in corpus
article 2026
The therapeutic potential of pirfenidone in alleviating fibrosis and restoring ovarian function in a novel ovarian endometriosis mouse model
Journal of translational medicine ·doi:10.1186/s12967-025-07648-z

BACKGROUND: Ovarian endometriosis (OEMs) is a primary cause of female infertility and is driven primarily by fibrosis, which disrupts the ovarian follicular microenvironment. Pirfenidone (PFD), an FDA-approved antifibrotic drug, holds promi…

2025
Machine learning-based preliminary screening tool for clinical pregnancy prediction: towards management of IVF/ICSI stages.
Annals of medicine ·doi:10.1080/07853890.2025.2582245

BackgroundAccurate prediction of pregnancy outcomes in assisted reproductive technology (ART) remains a clinical challenge due to the complexity and heterogeneity of IVF/ICSI cycles. Existing models often focus on isolated treatment stages …

article 2020
Circular RNA Expression Profiling and Bioinformatic Analysis of Cumulus Cells in Endometriosis Infertility Patients
Epigenomics ·doi:10.2217/epi-2020-0291

Aim: To explore the circular RNA (circRNA) profile in cumulus cells from endometriosis-associated infertility patients. Methods: The expression of circRNAs was profiled by high-throughput sequencing. Sanger sequencing was performed to ident…

article 2020
Differential expression of microRNA in exosomes derived from endometrial stromal cells of women with endometriosis-associated infertility
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2020.04.010

Research questionWhat is the expression pattern of microRNA (miRNA) in exosomes isolated from eutopic endometrial stromal cells (EuESC) of women with endometriosis-associated infertility?DesignSmall RNA sequencing was conducted in exosomes …