Fang Zhou

ORCID: 0000-0001-9581-9331 · 7 papers in corpus · active 2002-2024

Study types

  • article 6
  • preprint 1

Condition tags

  • endometriosis 3
  • adenomyosis 2
  • dysmenorrhea 1
  • infertility 1
article 2024
The Essential Role of PGF2α/PTGFR in Molding Endometrial Breakdown and Vascular Dynamics, Regulated by HIF-1α in a Mouse Menstrual-like Model
·doi:10.1007/s43032-024-01526-7
article 2023
A method for isolating and culturing ectopic epithelial and stromal cells to study human adenomyosis
Archives of gynecology and obstetrics ·doi:10.1007/s00404-023-07254-8

PURPOSE: Although adenomyosis is a common and benign gynecological disease, the specific pathogenesis of this condition is yet to be fully elucidated. It is difficult to culture primary cells of the ectopic endometrial epithelia and stroma …

preprint 2023
A method for isolating and culturing ectopic epithelial and stromal cells to study human adenomyosis
·doi:10.21203/rs.3.rs-3194957/v1

Abstract Purpose Although adenomyosis is a common and benign gynecological disease, the specific pathogenesis of this condition has yet to be fully elucidated. It is difficult to culture primary cells of the ectopic endometrial epithelia an…

article 2023
Long non coding RNA, C8orf49, a novel diagnostic and prognostic biomarker, enhances PTEN/FZD4-mediated cell growth and metastasis by sponging miR-1323 in endometriosis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2023.112040

Lack of sensitive biomarkers in the early stages of endometriosis (EMs) results in delayed diagnosis and intervention. Long non-coding RNAs (lncRNAs) have prognostic and diagnostic values in various diseases. However, the prognostic and dia…

article 2020
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway
·doi:10.1093/molehr/gaaa081

Polycystic ovary syndrome (PCOS) is the most common endocrinological pathology among women of reproductive age, whereas the pathogenesis is still not fully understood. Systemic and ovarian oxidative stress (OS) imbalance is a pivotal featur…

article 2020
Hypoxia: involved but not essential for endometrial breakdown in mouse menstural-like model
·doi:10.1530/rep-18-0562

Menstruation is a specific physiological phenomenon that occurs in women. However, molecular mechanisms underlying this phenomenon are still unclear. According to the classical theory, tissue hypoxia resulting from vasoconstriction of the s…

article 2002
Genetic or Enzymatic Disruption of Aromatase Inhibits the Growth of Ectopic Uterine Tissue
·doi:10.1210/jc.87.7.3460

Aromatase P450 (P450arom) is the key enzyme for the biosynthesis of estrogen that is essential for the growth of human endometriosis, a pathology characterized by endometrium-like tissue on the peritoneal surfaces of abdominal organs manife…