Verônica Coelho

ORCID: 0000-0002-0989-2581 · 4 papers in corpus
article 2024
Soluble MICA in endometriosis pathophysiology: impairs NK cell degranulation and effector functions

Problem: Endometriosis exhibits several immune dysfunctions, including deficient natural killer (NK) cell cytotoxicity. MICA (MHC class I chain-related molecule A) is induced by biological stress and soluble MICA (sMICA) negatively modulate…

article 2024
Soluble MICA in endometriosis pathophysiology: Impairs NK cell degranulation and effector functions
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13830

PROBLEM: Endometriosis exhibits several immune dysfunctions, including deficient natural killer (NK) cell cytotoxicity. MICA (MHC class I chain-related molecule A) is induced by biological stress and soluble MICA (sMICA) negatively modulate…

article 2020
Inhibitory KIR2DL2 Gene: Risk for Deep Endometriosis in Euro-descendants
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00255-x

Endometriosis (EDT) is an inflammatory disease characterized by implantation/growth of endometrial tissue, glands, and/or stroma, outside the uterus. Reduced NK cell cytotoxic activity has been implicated in its pathogenesis, together with …

article 2019
HLA-G is upregulated in advanced endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2019.01.030

ObjectiveTo assess whether the HLA-G immunomodulatory protein is potentially involved in the pathophysiology of endometriosis or disease progression.Study designCross-sectional observational study of 227 women who underwent laparoscopy, bei…