Andreana PR

No ORCID on file · 2 papers in corpus · active 2011-2014
2014
Journal of inorganic biochemistry ·doi:10.1016/j.jinorgbio.2014.06.018

Myeloperoxidase (MPO), lactoperoxidase (LPO) and eosinophil peroxidase (EPO) play a central role in oxidative damage in inflammatory disorders by utilizing hydrogen peroxide and halides/pseudo halides to generate the corresponding hypohalou…

2011
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2011.03.040

Here, we show that hypochlorous acid (HOCl), a potent neutrophil-generated oxidant, can mediate destruction of free heme (Ht) and the heme precursor, protoporphyrin IX (PPIX). Ht displays a broad Soret absorbance peak centered at 365 and 39…