Orhan Bukulmez

No ORCID on file · 8 papers in corpus · active 2007-2017

Study types

  • article 7
  • other 1

Condition tags

  • endometriosis 8
  • endometrioma 1
article 2017
Androgens Upregulate Endometrial Epithelial Progesterone Receptor Expression: Potential Implications for Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691145

BackgroundAndrogenic compounds have been implicated in induction of endometrial atrophy yet the mechanisms of androgen effects on human endometrium have not been well studied. We hypothesized that androgens may promote their endometrial eff…

article 2016
Endometrial miR-200c is Altered During Transformation into Cancerous States and Targets the Expression of ZEBs,

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Hereweassessed theexpression and functional aspectsofmiR-200c inendometrial tissues (N 52) fromnormal endometrial bi…

article 2016
Original Articles Endometrial miR-200c is Altered During Transformation into Cancerous States and Targets the Expression of ZEBs,

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Hereweassessed theexpression and functional aspectsofmiR-200c inendometrial tissues (N 52) fromnormal endometrial bi…

article 2013
0013-7227/08/$15.00/0 Endocrinology 149(3):1190–1204 Printed in U.S.A. Copyright © 2008 by The Endocrine Society doi: 10.1210/en.2007-0665 Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis

ENDOMETRIOSIS IS AN estrogen-dependent disease associated with enhanced aromatase expression and local estrogen production in endometriotic tissues (1–3). Although retrograde menstruation with subsequent implantation and growth of endometri…

other 2012
Endometrial miR-200c is altered during transformation into cancerous states and targets the expression of ZEBs, VEGFA, FLT1, IKKβ, KLF9, and FBLN5
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112438448

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Here we assessed the expression and functional aspects of miR-200c in endometrial tissues (N = 52) from normal endom…

article 2008
Androstenedione Up-Regulation of Endometrial Aromatase Expression via Local Conversion to Estrogen: Potential Relevance to the Pathogenesis of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-0248

CONTEXT: Up-regulation of aromatase expression in endometrial cells disseminated into the peritoneal cavity may enhance their survival via local estrogen synthesis, which may lead to endometriosis. The factors that mediate induction of arom…

article 2008
The Expression and Ovarian Steroid Regulation of Endometrial Micro-RNAs
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108324132

MicroRNAs (miRNAs) which regulate gene expression stability displayed an aberrant expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal endometrium (NE). We assessed the expression of miR-17-5p, miR-23a, mi…

article 2007
Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis
Endocrinology ·doi:10.1210/en.2007-0665

Aberrant up-regulation of aromatase in eutopic endometrium and implants from women with endometriosis has been reported. Aromatase induction may be mediated by increased cyclooxygenase-2 (COX-2). Recently, we demonstrated that progesterone …