Lei J

BackgroundIn vitro fertilization-embryo transfer (IVF-ET) remains a challenging treatment for infertility, particularly in patients with repeated implantation failures. Dalteparin sodium (DS), a low-molecular-weight heparin, has shown promi…

Infertility is a prevalent reproductive disorder, with local and systemic inflammatory responses potentially playing a pivotal role in its etiology. Alpha-1-acid glycoprotein (AGP), an acute-phase glycoprotein, has been implicated in inflam…

Ovarian cancer (OC) represents the most prevalent malignancy of the female reproductive system. Its distinguishing features include a high aggressiveness, substantial morbidity and mortality, and a lack of apparent symptoms, which collectiv…

Somatic mutations contribute to cancer development by altering the activity of enhancers. In the study, a total of 135 mutation-driven enhancers, which displayed significant chromatin accessibility changes, were identified as candidate risk…

Acute pancreatitis (AP) is a multifaceted inflammatory disorder stemming from the aberrant activation of trypsin within the pancreas. Despite the contribution of various factors to the pathogenesis of AP, such as trypsin activation, dysregu…

ObjectiveOur aim was to assess the accuracy of angiopoietin-2 (Ang-2) as a prognostic marker for acute pancreatitis (AP) with organ failure (OF).MethodsWe undertook a systematic search of the PubMed, Cochrane Library, Embase, Chinese Journa…

Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems but also play a role in other signal pathways by regulating additional MRGs. Because a MRG can regulat…