Charlotte Thieffry

No ORCID on file · 4 papers in corpus · active 2021-2023

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 3
  • adenomyosis 1
article 2023
Effects of estradiol, progesterone or cAMP on expression of PGRMC1 and progesterone receptor in a xenograft model of human endometrium and in endometrial cell culture
Steroids ·doi:10.1016/j.steroids.2023.109284

Estradiol and progesterone are key regulators of the menstrual cycle. In the human endometrium, progesterone induces morphological changes required for blastocyst implantation. Dysregulated response to progesterone can lead to endometrial p…

article 2022
P-297 Regulation and functions of PGRMC1 in the human endometrium and in endometriosis
·doi:10.1093/humrep/deac107.284

Abstract Study question What is the role of PGRMC1 in the human endometrium (especially in tissue remodeling) and its potential contribution to the development of endometrial diseases? Summary answer In primary endometrial stromal cell cult…

article 2022
Spatiotemporal expression pattern of Progesterone Receptor Component (PGRMC) 1 in endometrium from patients with or without endometriosis or adenomyosis
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2022.106153

The endometrium plays a crucial role in reproduction and, in humans, is cyclically remodeled under hormonal control. Estradiol favors tissue proliferation whereas progesterone inhibits tissue growth and induces morphological changes. Endome…

other 2021
AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins
Biomolecules ·doi:10.3390/biom11101472

An inappropriate response to progestogens in the human endometrium can result in fertility issues and jeopardize progestin-based treatments against pathologies such as endometriosis. PGRMC1 can mediate progesterone response in the breast an…