Liu L

ObjectiveTo investigate whether vaginal and endometrial microbiota impact pregnancy outcomes in frozen embryo transfers (FET) during hormone replacement cycles.MethodsThis retrospective cohort study analyzed 51 first-time FET patients from …

PurposeTo evaluate the value of mtDNA copy number measurement in spent culture medium of blastocysts for predicting the chance of implantation following single blastocyst transfer (SBT).MethodsCopy numbers of mtDNA and genomic DNA (gDNA) we…

Objectives: To investigate the diagnostic performance of texture analysis using multi-parameter MRI in distinguishing between benign and malignant lesions with ovarian-adnexal magnetic resonance imaging report and data system (O-RADS MRI) s…

Endometriosis is a common estrogen-dependent gynecological disorder characterized by chronic inflammatory responses and frequently associated with clinical infertility. Recent studies have demonstrated that the pathogenesis of this disease …

BackgroundE2 is important in follicular development. During monitoring of stimulated cycles, serum levels of E2 are expected to increase steadily with follicle growth until final maturation. Unexpected E2 decline before triggering is report…

BackgroundOvarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an essential regulator in cancer metabolism, whose functions are still unknown in OC. Therefore, it i…

PurposeThis study aimed to develop a predictive model for assessing clinical pregnancy probabilities in patients undergoing frozen-thawed cycles with single Day 6 blastocyst transfers.MethodsWe conducted a two-center retrospective cohort st…

ObjectiveTo investigate the interaction between atosiban and growth hormone (GH) as adjuvants in frozen-thawed embryo transfer (FET) cycles.MethodA total of 11627 patients who underwent FET at Xiamen University Affiliated Chenggong Hospital…

BackgroundLow-dose aspirin is one of the widely used adjuvants in assisted reproductive technologies with the hope of improving the live birth rate. However, the studies regarding its effects are conflicting. The study aimed to investigate …

OBJECTIVE: To investigate the causal effect of immune cells on endometriosis (EMS), we performed a Mendelian randomization analysis. METHODS: Mendelian randomization (MR) uses genetic variants as instrumental variables to investigate the c…

Endometriosis (EMs) is a common gynecological disease accompanied by metabolic disturbances. However, the causality between metabolites and the risk of EMs remains unclear. We conducted a 2-sample Mendelian randomization (MR) analysis using…

BackgroundThe low live birth rate and difficult decision-making of the in vitro fertilization (IVF) treatment regimen bring great trouble to patients and clinicians. Based on the retrospective clinical data of patients undergoing the IVF cy…

Ovarian cancer, a group of heterogeneous diseases, presents with extensive characteristics with the highest mortality among gynecological malignancies. Accurate and early diagnosis of ovarian cancer is of great significance. Here, we presen…

PurposeDecreased ovarian reserve function is mainly characterized by female endocrine disorders and fertility decline. Follicular fluid (FF) exosomal microRNAs (miRNAs) have been shown to regulate the function of granulosa cells (GCs). The …

PurposeTo evaluate the contribution of the cleavage stage morphological parameters to the prediction of blastocyst transfer outcomes.MethodsA retrospective study was conducted on 8383 single-blastocyst transfer cycles including 2246 fresh a…

ObjectivesTo evaluate the effectiveness and safety of Chinese herbal footbaths (CHF) as an adjunctive therapy in managing dysmenorrhea.MethodsTen electronic databases were searched to identify eligible randomized clinical trials (RCTs) from…

BackgroundEndometrial carcinoma (EC) is a prevalent gynecological malignancy, necessitating accurate preoperative staging for effective treatment planning. This study explores the application value of multi-parameter MRI in diagnosing and s…

OBJECTIVES: To observe the therapeutic efficacy of high-intensity focused ultrasound (HIFU) combined with different pharmacological treatments for adenomyosis. MATERIALS AND METHODS: A total of 126 patients with adenomyosis who underwent H…

ObjectiveInvestigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for distinguishing between benign and malignant ovarian tumors.MethodsIn this study, we selected a total of 234 patients…

BACKGROUND: Endometriosis (EMT) is a common disease in reproductive-age woman and Crohn disease (CD) is a chronic inflammatory disorder in gastrointestinal tract. Previous studies reported that patients with EMT had an increased risk of CD.…

BACKGROUND: Numerous observational studies and randomized controlled trials have recently revealed the associations between circulating antioxidants and the risk of endometriosis, while the underlying causal relationship remains unclear. Th…

BackgroundPlacental anomalies, including placenta previa (PP), placenta accreta spectrum disorders (PAS), and vase previa (VP), are associated with several adverse foetal-neonatal and maternal complications. However, there is still a lack o…

​Mucinous ovarian cancer (MOC) is characterized by high malignancy, poor prognosis and a high recurrence rate. Surgical adjuvant chemotherapy is the main treatment for MOC. The recurrence rate of advanced mucinous ovarian cancer following s…

PurposeTo investigate the impact of heterogeneity in patient indications or insemination protocols on neonatal outcomes of singletons following early rescue ICSI (rICSI) treatments.MethodsA retrospective study was conducted. Propensity scor…