The development of novel therapies for endometriosis is a rapidly evolving field, encompassing diverse approaches to address this complex and chronic condition. Current treatment modalities, predominantly hormonal therapies and surgical int…
Endometriosis is a persistent inflammatory condition characterised by chronic pain, increasing the chances of infertility and adverse pregnancy outcomes. However, the existing evidence on this matter lacks consistency. The disease is associ…
A biosensor was developed for the quantification of poly(ADP-ribose) polymerase-1 (PARP-1) in body fluids. An antibody specific for PARP-1 was placed on a chip with cysteamine (linker) and a gold layer. This biosensor has a linear response …
We would like to announce a new vision of the Journal of Endometriosis and Pelvic Pain Disorders. Thanks to the contribution by former Editors-in-Chief, Associate Editors, and Editorial Board members, as well as all Readers we have a stable…
INTRODUCTION: Endometriosis is an inflammatory-related reproductive age disease characterized by the presence of endometrial cells outside the uterine cavity. Current laboratory practice does not provide specific markers for detecting and a…
Previously, the gold standard for the diagnosis of endometriosis involved the performance of laparoscopic surgery, which allows the visualization and histological examination of the endometrial tissue. According to the latest guidelines pub…
Zinc finger E-box-binding homeobox 1 (ZEB1) and zinc finger E-box-binding homeobox 2 (ZEB2) are transcription factors that regulate epithelial−mesenchymal transformation (EMT). The aim of this study was to compare levels of ZEB1 and ZEB2 in…
The evidence of poly (ADP-ribose) polymerase (PARP) association with the immune response could be coherent with the immunological theory of endometriosis and suggests the possibility of a new research direction. The aim of the study was to …
Cadherin 12 (CDH 12) can play a role in the pathogenesis of endometriosis. The aim of this study was to compare the levels of cadherin 12 in the peritoneal fluid between women with and without endometriosis. This was a multicenter cross-sec…