Yi Li

Endometriosis is a common gynecological disorder characterized by the ectopic growth of endometrium-like tissue outside the uterine cavity and is associated with pelvic pain, infertility, and reduced quality of life. Although several theori…

OBJECTIVE: This study aimed to delineate the clinical characteristics of endometriosis patients with dysmenorrhea and analyze the correlations between the presence, severity, and duration of dysmenorrhea and the severity of endometriosis. …

Spontaneous uterine rupture outside of pregnancy is exceptionally rare, with adenomyosis potentially acting as a structurally weakening substrate. Most reports involve gravid patients, underscoring the unusual nature of nongravid presentati…

PURPOSE: To elucidatethe epigenetic alteration associated with impaired oogenesis in endometrioma using multi-omic approaches. METHODS: ATAC-seq was performed on the granulosa cells (GCs) of 6 patients (3 with endometrioma and 3 without). …

Extracellular matrix protein 1 (ECM1) is a glycoprotein that may be a key player in tumorigenesis and tumor progression. However, knowledge regarding the role of ECM1 in endometriosis (EM) is still lacking. Microarray analyses were performe…

Objective: To investigate the familial heritability of endometriosis and to compare the clinical characteristics of patients with or without a family history of endometriosis. Methods: From January 2020 to June 2022, 850 patients with endom…

Abstract Pompe disease (PD) is a rare autosomal-recessive glycogen storage disorder resulting in proximal muscle weakness and loss of respiratory function. While enzyme replacement therapy (ERT) is the only effective treatment, biomarkers …

Adenomyosis is an estrogen-dependent gynecological disorder. The abnormal migration and invasion of the eutopic endometrium is thought to be the primary role in the pathogenesis of adenomyosis. However, the exact underlying mechanism remain…

Abstract Objectives Previous studies demonstrated that endometriosis and adenomyosis are closely linked to lots of adverse pregnancy outcomes while the role of endometriosis in pregnant women with adenomyosis has not been explored yet. The …

Background: Acute severe organophosphorus pesticide poisoning (ASOPP) is a common severe emergency in developing countries. At present, the incidence of complications and mortality are still very high, and there are some difficulties in tr…

(Abstracted from Fertil Steril 2019;112:1103–1111) Chronic endometriosis (CE) is a chronic infectious disease that is often misdiagnosed due to its vague symptomatic severity, lack of typical clinical or ultrasounds symptoms, and requiremen…

Background: People living with HIV/AIDS not only require effective treatment for the alleviation of physical discomfort but also require social support to help them address difficulties in life and relieve their psychological anxiety and u…

BACKGROUND: The association between the previous history of endometriosis and obstetric outcomes is still ambiguous. This study aimed to evaluate the effects of previous history of operatively diagnosed endometriosis on pregnancy outcomes. …

BACKGROUND: We investigated possible biomarkers for endometriosis (EM) using the ClinProt technique and proteomics methods. METHODS: We enrolled 50 patients with EM, 34 with benign ovarian neoplasms and 40 healthy volunteers in this study. …

OBJECTIVE: To analyze the recurrence and fertility outcome of stage III - IV endometriosis after conservative surgery. METHODS: A retrospective study was performed on 90 women with stage III - IV endometriosis who had been diagnosed by path…

To observe the changes of the number and localization of mast cells and eosinocytes in ectopic endometrium from EMT model rats and to study the relationship between mast cells, eosinocytes and endometriosis. Rat endometriosis model was esta…