Ruolin WANG

No ORCID on file · 2 papers in corpus · active 2025-2026

Study types

  • article 2

Condition tags

  • endometriosis 2
article 2026
A mechanistic study of <italic>Zishen Quyu Jiedu Formula </italic>（滋肾祛瘀解毒方） in alleviating oxidative stress in endometriosis rats via the Nrf2/HO-1 signaling pathway
·doi:10.70976/j.1008-0805.szgygy-2026-0502

目的 探讨滋肾祛瘀解毒方通过调控NRF2-HO1信号通路改善子宫内膜异位症（EMs）的作用，并从氧化应激角度阐明中医药治疗EMs的机制。 方法 将40只健康未孕SD雌性大鼠随机分为空白组10只、模型组10只，米非司酮组10只，滋肾祛瘀解毒方组10只。使用自体移植法建立大鼠EMs模型，HE染色观察子宫内膜异位病灶组织形态变化；免疫组化法检测 NRF2、HO1、NQO1在细胞中的阳性表达；ELISA法检测大鼠血清SOD、MDA、GSH-PX、8-epi-PGF2α、IL-6…

article 2025
Exploring the mechanism of Zishen Quyu Jiedu formula in treating endometriosis based on network pharmacology and experimental verification
Frontiers in endocrinology ·doi:10.3389/fendo.2025.1667486

OBJECTIVE: Zishen Quyu Jiedu formula (ZQYJDF) is a commonly used prescription for endometriosis (EMs) with clinical efficacy. However, its active components and potential mechanisms remain unknown. This study aimed to identify the key targe…