Ko C

No ORCID on file · 6 papers in corpus · active 2011-2020

Study types

  • article 1

Condition tags

  • irritable_bowel_syndrome 2
  • endometriosis 1
2020
Relationships of Microbiome Markers With Extraintestinal, Psychological Distress and Gastrointestinal Symptoms, and Quality of Life in Women With Irritable Bowel Syndrome.
Journal of clinical gastroenterology ·doi:10.1097/mcg.0000000000001107

IntroductionAltered microbial diversity has been associated with gastrointestinal (GI) symptoms in persons with irritable bowel syndrome (IBS). Less is known about the relationship of microbiome with extraintestinal pain and psychological d…

2019
Ovulation: Parallels With Inflammatory Processes.
Endocrine reviews ·doi:10.1210/er.2018-00075

The midcycle surge of LH sets in motion interconnected networks of signaling cascades to bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators of these LH-induced signaling cascades are associated wi…

2018
Stool and urine trefoil factor 3 levels: associations with symptoms, intestinal permeability, and microbial diversity in irritable bowel syndrome.
Beneficial microbes ·doi:10.3920/bm2017.0059

Previously we showed that urine trefoil factor 3 (TFF3) levels were higher in females with irritable bowel syndrome (IBS) compared to non-IBS females. To assess if TFF3 is associated with symptoms and/or reflect alterations in gastrointesti…

article 2015
Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis
Science translational medicine ·doi:10.1126/scitranslmed.3010626

Estrogenic and inflammatory components play key roles in a broad range of diseases including endometriosis, a common estrogen-dependent gynecological disorder in which endometrial tissue creates inflammatory lesions at extrauterine sites, c…

2012
Hematopoetic prostaglandin D synthase: an ESR1-dependent oviductal epithelial cell synthase.
Endocrinology ·doi:10.1210/en.2011-1900

Oviductal disease is a primary cause of infertility, a problem that largely stems from excessive inflammation of this key reproductive organ. Our poor understanding of the mechanisms regulating oviductal inflammation restricts our ability t…

2011
Expression pattern of endothelin system components and localization of smooth muscle cells in the human pre-ovulatory follicle.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/der066

BackgroundWhether ovarian follicular rupture involves contractile activity or not has been debated for decades. Recently, study in the rodents has indicated that an endogenously produced potent vasoconstrictive peptide, endothelin-2 (EDN2),…