Y Shibutani

No ORCID on file · 7 papers in corpus · active 1997-2017

Study types

  • article 7

Condition tags

  • endometriosis 4
article 2017
Effect of Genistein, Leuprolide Acetate and Dienogest towards Progesterone Receptor, IL-8, MMP-2 Expression of Lesions in a Peritoneal Mice Model of Endometriosis
·doi:10.20902/ijptr.2018.11110

Endometriosis is estrogen-dependent disease that is related to the inflammatory process in the peritoneal cavity. To being activated by pro-inflammatory cytokines, endometriosis is also influenced by the response of progesterone receptors. …

article 1999
Dienogest, a synthetic steroid, suppresses both embryonic and tumor-cell-induced angiogenesis
European journal of pharmacology ·doi:10.1016/s0014-2999(99)00765-7
article 1999
Effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats
Toxicology letters ·doi:10.1016/s0378-4274(98)00354-3
article 1998
Effects of dienogest (a synthetic steroid) on coagulation, fibrinolysis, and platelet aggregation in female monkeys
·doi:10.1016/s0378-4274(98)00109-x
article 1998
Effects of dienogest, a synthetic steroid, on experimental endometriosis in rats
European journal of endocrinology ·doi:10.1530/eje.0.1380216

OBJECTIVE: Dienogest, a synthetic steroid with progestational activity, is used as a component of oral contraceptives and is currently being evaluated clinically for the treatment of endometriosis. The present study was conducted to confirm…

article 1997
Animal studies on the endocrinological profile of dienogest, a novel synthetic steroid.
Drugs under experimental and clinical research

Dienogest is an orally active synthetic steroid that is used for contraception and is currently being studied for the possible treatment of endometriosis. Earlier we demonstrated that dienogest had therapeutic effects on experimental endome…

article 1997
Dienogest, a novel synthetic steroid, overcomes hormone-dependent cancer in a different manner than progestins
Cancer ·doi:10.1002/(sici)1097-0142(19970101)79:1<169::aid-cncr24>3.0.co;2-1

BACKGROUND: Dienogest is a synthetic progestational steroid that is used for contraception. It is being studied for the treatment of endometriosis, but its anticancer activity remains unknown. The authors investigated the anticancer effect …