Nannan Kang

No ORCID on file · 9 papers in corpus · active 2021-2026

Study types

  • article 4
  • preprint 3
  • other 2

Condition tags

  • endometriosis 7
  • infertility 4
  • adenomyosis 2
other 2026
Glycolytic reprogramming and MYH10 K1520 lactylation mediate eutopic endometrial collagen I deposition driven by PKM2-packaged ectopic endometrial extracellular vesicles
Molecular human reproduction ·doi:10.1093/molehr/gaag028

Endometriosis (EMs) is characterized by ectopic lesions that disrupt endometrial decidualization, a process frequently accompanied by aberrant collagen deposition and closely linked to clinical infertility. Extracellular vesicles (EVs) are …

article 2024
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gaae042

Endometrial collagen I undergoes dynamic degradation and remodelling in response to endometrial stromal cell (ESC) decidualization and embryo implantation. However, excessive collagen I deposition in the endometrium during the implantation …

preprint 2023
Endometriotic Stromal Cell-Derived Exosomal miR-25-3p Induces Endometrial Collagen Ⅰ Deposition Impairing Decidualization And Embryo Implantation via Targeting PTEN in Endometriosis
·doi:10.2139/ssrn.4325256
article 2022
Calpain7 negatively regulates human endometrial stromal cell decidualization in EMs by promoting FoxO1 nuclear exclusion via hydrolyzing AKT1
Biology of reproduction ·doi:10.1093/biolre/ioac041

Endometrial receptivity damage caused by impaired decidualization may be one of the mechanisms of infertility in endometriosis (EMs). Our previous study demonstrated that Calpain-7 (CAPN7) is abnormally overexpressed in EMs. Whether CAPN7 a…

other 2022
Endometrial stromal PRMT5 plays a crucial role in decidualization by regulating NF-κB signaling in endometriosis
Cell death discovery ·doi:10.1038/s41420-022-01196-x

Decidualization is a prerequisite for successful embryo implantation, in which elongated fibroblast-like endometrial stromal cells differentiate into more rounded decidual cells. Accumulating evidence has stressed the important role of the …

preprint 2022
Endometrial stromal PRMT5 plays a crucial role in decidualization by regulating NF-κB signaling in endometriosis
·doi:10.21203/rs.3.rs-1800392/v1
article 2022
Transcriptome analysis of eutopic endometrium in adenomyosis after GnRH agonist treatment
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00881-3

BACKGROUND: Adenomyosis is a chronic gynecological disease characterized by invasion of the uterine endometrium into the muscle layer. In assisted reproductive technology (ART), gonadotropin-releasing hormone agonist (GnRHa) is often used t…

article 2021
Attenuated monoamine oxidase a impairs endometrial receptivity in women with adenomyosis via downregulation of FOXO1
Biology of reproduction ·doi:10.1093/biolre/ioab182

The establishment of endometrial receptivity is a prerequisite for successful pregnancy. Women with adenomyosis possess a lower chance of clinical pregnancy after assisted reproductive technology, which is partially due to impaired endometr…

preprint 2021
Calpain7 Negatively Regulates Human Endometrial Stromal Cell Decidualization in Endometriosis by Promoting FoxO1’s Phosphorylation and Nuclear Exclusion via Hydrolyzing AKT1
·doi:10.21203/rs.3.rs-985926/v1

Abstract Background Endometrial receptivity damage caused by impaired decidualization may be one of the mechanisms of infertility in endometriosis (EMs). Our previous study demonstrated that Calpain-7 (CAPN7) is abnormally overexpressed in …