Zhu X

ORCID: 0000-0002-4376-0806 · 125 papers in corpus
review 2021
Frontiers in oncology ·doi:10.3389/fonc.2021.745808

Ovarian cancer ranks as the fifth most common cause of cancer-related death in females. The molecular mechanisms of ovarian carcinogenesis need to be explored in order to identify effective clinical therapies for ovarian cancer. Recently, m…

observational 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.669507

BACKGROUND: Early cumulus cell removal combined with early rescue intracytoplasmic sperm injection (ICSI) has been widely practiced in many in vitro fertilization (IVF) centers in China in order to avoid total fertilization failure. However…

other 2021
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group ·doi:10.1080/02656736.2021.1886347

OBJECTIVE: To investigate the long-term clinical outcomes of patients with adenomyosis treated by high-intensity focused ultrasound (HIFU). MATERIALS AND METHODS: From June 2012 to January 2020, 2311 patients with adenomyosis were treated …

other 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00713-4

BACKGROUND: While heavy menstrual bleeding (HMB) is a prevalent symptom among women with abnormal uterine bleeding caused by endometrial disorder (AUB-E) seeking gynecologic care, the primary endometrial disorder remains poorly understood. …

other 2021
JCI insight ·doi:10.1172/jci.insight.132585

Hyperstimulation of the cholecystokinin 1 receptor (CCK1R), a G protein-coupled receptor (GPCR), in pancreatic acinar cells is commonly used to induce pancreatitis in rodents. Human pancreatic acinar cells lack CCK1R but express cholinergic…

rct 2021
Annals of translational medicine ·doi:10.21037/atm-20-1592

BACKGROUND: Exogenous progestational agents have recently been introduced as an alternative pituitary modulator for the prevention of premature luteinizing hormone (LH) surges during in vitro fertilization (IVF)/intracytoplasmic sperm injec…

observational 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00825-x

BACKGROUND: Diminished ovarian reserve (DOR) refers to a decrease in the number and quality of oocytes in the ovary, which results in a lack of sex hormones and a decline of fertility in women. DOR can potentially progress to premature ovar…

lab-animal 2020
Nature communications ·doi:10.1038/s41467-020-18638-8

High-altitude adaptation of Tibetans represents a remarkable case of natural selection during recent human evolution. Previous genome-wide scans found many non-coding variants under selection, suggesting a pressing need to understand the fu…

other 2020
Medicine ·doi:10.1097/md.0000000000019044

INTRODUCTION: The purpose of this study is to evaluate the efficacy and safety of acupuncture on relieving abdominal pain and distension in acute pancreatitis. METHODS AND ANALYSIS: We will electronically search PubMed, MEDLINE, Embase, We…

observational 2020
Advances in therapy ·doi:10.1007/s12325-020-01361-7

INTRODUCTION: To compare all-cause and endometriosis-related healthcare resource utilization (HCRU) and healthcare costs by service categories (outpatient, inpatient, emergency room [ER], pharmacy) among patients with newly diagnosed endome…

lab-animal 2020
Cancer cell international ·doi:10.1186/s12935-020-01347-z

BACKGROUND: Alpha protein kinase 2 (ALPK2) was known to play a vital role in cancer by regulating cell cycle and DNA repair. Ovarian cancer (OC) is one of the most lethal malignancies in the female reproductive system. The emphasis of this …

other 2020
Journal of biological regulators and homeostatic agents ·doi:10.23812/20-249-l
lab-animal 2020
Molecular therapy. Methods & clinical development ·doi:10.1016/j.omtm.2020.09.013

Endometriosis is a benign disease that shares some malignant features. Epithelial-mesenchymal transition (EMT) is involved in the pathogenesis of endometriosis. Metastasis-associated protein 1 (MTA1) plays an important role in various cance…

2020
·doi:10.21203/rs.3.rs-117894/v1

Abstract BackgroundCoronavirus Disease 2019 (COVID-19) respiratory disease rapidly caused a global pandemic and social and economic disruption. The combination of Traditional Chinese medicine (TCM) and Conventional Western medicine (CWM) i…

lab-animal 2020

Wenbin Xu,1,* Yizuo Song,1,* Kehan Li,1 Biyun Zhang,2 Xueqiong Zhu1 1Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, People’s Republic of China; 2Department of…

observational 2020
Annals of translational medicine ·doi:10.21037/atm.2019.11.124

BACKGROUND: Intrauterine adhesion (IUA) is one of the most important causes of female infertility, while iatrogenic endometrial injury is the main, but not the entire, cause of IUA. The microorganisms of the female reproductive tract play a…

meta-analysis 2020
Disease markers ·doi:10.1155/2020/1075942

BACKGROUND: Ovarian cancer is the 5th leading cause of death of women due to cancer in the United States. Although carbohydrate antigen 125 has a moderate diagnostic utility, the phenomenon of false-positive exists. As novel effective bioma…

observational 2020
Women's health (London, England) ·doi:10.1177/1745506520965898

OBJECTIVES: Evaluate all-cause and endometriosis-related health care resource utilization and costs among newly diagnosed endometriosis patients with high-risk versus low-risk opioid use or patients with chronic versus non-chronic opioid us…

meta-analysis 2020
BMC pregnancy and childbirth ·doi:10.1186/s12884-020-03248-5

BACKGROUND: In recent years, there have been many reports on the pregnancy outcomes of fresh blastocyst transfer (BT) and frozen-thawed BT, but the conclusions are controversial and incomplete. To compare the pregnancy outcomes, maternal co…

other 2019
Frontiers in endocrinology ·doi:10.3389/fendo.2019.00325

Background: The ability of anti-Müllerian hormone (AMH) to predict ovarian response has been studied extensively in gonadotropin-releasing hormone agonist and antagonist treatments, but no information is available regarding its value in pro…

other 2019
Frontiers in endocrinology ·doi:10.3389/fendo.2019.00448

Objective: To investigate the feasibility of ovarian stimulation initiated in the late follicular phase using human menopausal gonadotropin (hMG) alone in ovulatory patients undergoing in vitro fertilization (IVF)/intracytoplasmic sperm inj…

lab-animal 2019
International journal of molecular medicine ·doi:10.3892/ijmm.2019.4370

Endometriosis is associated with changes in long non‑coding RNA (lncRNA) and mRNA expression, but the exact changes during the implantation window are unknown. Therefore, this study aimed to explore the lncRNA and mRNA expression profiles i…

rct 2019
Frontiers in endocrinology ·doi:10.3389/fendo.2019.00875

Purpose: To illustrate whether low-dose human chorionic gonadotropin (hCG) administration during the early follicular phase could reduce the number of large preovulatory follicles in women with polycystic ovarian syndrome (PCOS) undergoing …

2019
The Cochrane database of systematic reviews
review 2018
OncoTargets and therapy ·doi:10.2147/ott.s159829

Ovarian cancer is the leading cause of female gynecological cancer mortality. Most patients with ovarian cancer are diagnosed with advanced stage because of lack of early symptoms, physical signs, and sensitive tumor biomarkers. The standar…