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The increasing association of insulin resistance (IR) with severe mental illnesses has a lot of importance to mental health and metabolism. Researching the association between IR indices and anxiety is quite fragmented. This study included …

OBJECTIVE: This study aims to propose a novel, reproducible transvaginal ultrasound (TVUS) measurement-anterior-posterior wall thickness of the uterine isthmus ratio (APTUIR)-and to construct a nomogram model integrating this parameter with…

Deep infiltrating endometriosis (DIE) and focal adenomyosis of the outer myometrium (FAOM) are closely related chronic inflammatory conditions that often coexist. The systemic immune-inflammation index (SII), systemic inflammation response …

Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited b…

BACKGROUND: Deeply infiltrating endometriosis (DIE), characterized by its extrauterine invasion, is strongly associated with chronic pelvic pain (CPP). Peripheral-central sensitization synergistically contribute to the pathogenesis of CPP i…

BACKGROUND Postoperative sleep disturbances are common after gynecological laparoscopic surgery, possibly delaying recovery. This study evaluated whether additional postoperative administration of dexmedetomidine hydrochloride nasal spray c…

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apop…

Recurrent implantation failure (RIF), characterized by repeated failure to achieve clinical pregnancy after embryo transfer, is often associated with abnormal endometrial conditions. However, unexplained RIF is unique in that its underlying…

This study aimed to investigate how levels of serum follicle-stimulating hormone (FSH) on Day 7 of ovarian stimulation are related to the number of oocytes retrieved, and identify any cutoff or threshold point in protocols using gonadotropi…

BACKGROUND: Endometriosis (EMS) is an oestrogen-dependent chronic inflammatory disease that primarily manifests as chronic pelvic pain and infertility. EMS-associated infertility is closely linked to diminished ovarian function and oocyte q…

BACKGROUND: N6-methyladenosine (m6A) modification regulates the processes of RNA splicing, subcellular localization, translation and stability by changing the RNA structure and the interaction between RNA and RNA-binding proteins to ensure …

Study questionDoes intercornual distance (ICD), as reflected by intrauterine stent size during hysteroscopic adhesiolysis, have an association with reproductive outcomes and provide information for postoperative risk stratification in women…

RESEARCH QUESTION: Is surgery effective in decreasing iron deposition in the ovarian tissue surrounding an ovarian endometrioma? DESIGN: This cohort study was conducted in China between July 2023 and April 2024. Seventy-nine patients with …

Gestational diabetes mellitus (GDM), is a prevalent metabolic disorder associated with placental dysfunction and adverse pregnancy outcomes. Emerging evidence points to endoplasmic reticulum (ER) stress as a potential initiating factor in G…

Metabolism-regulating microspheres have evolved from conventional drug carriers into active platforms capable of spatiotemporally reprogramming pathological metabolic networks. Chronic diseases are increasingly understood to be driven by me…

Objectives: Although blastocyst transfer may improve embryo selection and early pregnancy outcomes, its impact on live birth in women with recurrent implantation failure (RIF) remains uncertain. This study compared reproductive and perinata…

BACKGROUND: Endometriosis is a common estrogen-dependent disorder that typically affects women of reproductive age and generally resolves following menopause. This report describes a rare case of postmenopausal bladder endometriosis (BE) oc…

Abstract Background Endometriosis is a common estrogen-dependent disorder that typically affects women of reproductive age and generally resolves following menopause. This report describes a rare case of postmenopausal bladder endometrios…

Endometriosis (EMs) is an estrogen-dependent, chronic inflammatory disorder characterized by immune microenvironment dysregulation, a critical factor in its pathogenesis. Despite existing therapies, limitations persist, highlighting the urg…

BackgroundInfertility affects many couples worldwide, and the accurate assessment of endometrial receptivity (ER) is critical. However, conventional ultrasound has limited predictive value. Multiparameter quantitative ultrasound is a promis…

BackgroundAbnormalities in ureteral motility often precede morphological changes, and early subtle lesions are easily overlooked, thereby increasing the risk of renal impairment. However, existing imaging assessments tend to focus on qualit…

PurposeTo investigate the impact of regressed endometrial hyperplasia (EH) on assisted reproductive technology outcomes, particularly in comparison with infertile women with a relatively normal endometrium.MethodsThis retrospective study in…

N6-methyladenosine (m6A) is a critical regulator of female reproductive physiology, yet existing reviews have focused predominantly on oocytes. The objective of this review is to systematically evaluate the regulatory effects of m6A through…

BACKGROUND: Adenomyosis (AM) is a common benign gynecological disease, defined by the presence of endometrial glands and stroma deep within the myometrium, which is associated with hypertrophy and hyperplasia of the adjacent myometrium. It …