Lan Chao

No ORCID on file · 5 papers in corpus
article 2022
Biology of reproduction ·doi:10.1093/biolre/ioac151

The processes underlying adenomyosis are similar to those of tumor metastasis, and it is defined as progressive invasion by the endometrium and the subsequent creation of ectopic lesions. GRIM-19 regulates cell death via the mitochondrial r…

article 2021
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2021.10.012

Research questionDoes the absence of GRIM19 affect pyroptosis of macrophages? Is the release of IL-1β caused by pyroptosis a relevant factor in the regulation of adenomyosis progression?DesignEndometrial tissues were collected from patients…

article 2021
Reproduction (Cambridge, England) ·doi:10.1530/rep-21-0181

The epithelial-to-mesenchymal transition may play a role in adenomyosis. GRIM19 expression is downregulated in adenomyotic lesions, and the effects of this downregulation in adenomyosis remain relatively unclear. In this study, we aimed to …

article 2020
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2020.04.022

Research questionDoes the aggregation of M2 macrophages affect the expression of gene associated with retinoid-interferon-induced mortality 19 (GRIM-19) in adenomyosis?DesignEndometrial tissues were collected from patients with (n = 15) and…

other 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.12.019

OBJECTIVE: To study the expression of the gene associated with retinoid-interferon (IFN)-induced mortality 19 (GRIM-19) in the endometrial tissue of patients with adenomyosis and to describe the possible pathogenic mechanisms of this phenom…