Li Liu

Endometriosis is a chronic estrogen-dependent gynecological disorder characterized by the ectopic growth of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age worldwide. It is a lead…

Abstract Objectives This study investigated the fertilizing potential of leuprolide acetate in infertile patients with endometriosis (EMS). Methods This study included 116 patients with the EMS infertility, who were randomly divided into th…

Endometriosis (EMs), a common and frequently occurring gynecological disease, is a major cause of chronic pelvic pain and infertility in women. Its pathogenesis remains unclear to date, and it is characterized by high invasiveness and recur…

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic or danger-associated signals…

Endometriosis is characterized by aberrant epigenetic regulation, and our study reveals that both Ubiquitin Specific Protease 7 (USP7) and DNA methyltransferase 1 (DNMT1) are significantly overexpressed in endometriosis tissues. Functional …

OBJECTIVE: To investigate the causal effect of immune cells on endometriosis (EMS), we performed a Mendelian randomization analysis. METHODS: Mendelian randomization (MR) uses genetic variants as instrumental variables to investigate the c…

BACKGROUND: Endometriosis patients exhibit a cancer-like glycolytic phenotype. The pyruvate kinase M2 (PKM2)/hypoxia-inducible factor-1 alpha (HIF-1α) axis plays important roles in glycolysis-related diseases, but its role in patients with …

Along with the advancement of science and technology and the ongoing development of adjuvant therapies, the treatment options for common or difficult diseases related to gynecology have become more diversified.

Background: Adenomyosis (AM) is a common benign uterine disease that threatens the normal life of patients. Cells associated with microenvironmental immune ecology are crucial in AM, although they are not as well understood at the cellular …

This study aimed to uncover effects of non-coding RNA transcripts on ovarian endometriosis (OEM) development. Two transcription datasets (GSE105764 and GSE105765) about OME were downloaded from Gene Expression Omnibus (GEO) database and the…

Abstract Background Alzheimer’s disease (AD) is the most common cause of dementia, accounting for an estimated 60 to 80% of cases, and is the sixth-leading cause of death in the United States. While considerable advancements have been mad…

Background: Increasing evidence suggests that centromere-associated protein E (CENP-E) is expressed during mitosis and plays a key role in incorrect chromosome alignment. Therefore, CENP-E may represent a druggable target for several solid…

Adenomyosis is a common chronic gynecological disorder with some tumor-like properties, including aberrant proliferation, invasion and migration. Berberine (BBR) is an isoquinoline derivative alkaloid with diverse pharmacological activities…

A previous study by our group has demonstrated that lipopolysaccharide (LPS) induces adenomyosis through stimulating inflammatory cell proliferation and invasive growth of stromal cells via Toll-like receptor 4 (TLR4) signaling. The present…

Study objectiveTo evaluate safety, feasibility, and long-term clinical effects of adding laparoscopic pelvic plexus ablation to uterine-sparing procedures (uterine artery occlusion and partial adenomyomectomy) for adenomyosis.DesignA prospe…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…

The invention pertains to the field of traditional Chinese medicine preparations, in particular to a medicine preparation for treating endometriosis and a preparation method thereof. The medicine preparation takes the traditional Chinese me…