Fang Zhao

GLI1 and Shh are highly associated with the malignant transformation of ovarian EM, which may play a role in promoting malignant degeneration of ovarian EM, and the high expression of GLI1 and Shh indicates a poor prognosis in EAOC patients…

子宫内膜乳头状黏液性化生是一种相对少见的子宫内膜黏液性化生性病变，被认为可能是低级别子宫内膜腺癌的癌前病变。由于细胞学异型性和结构变化的差异性较大，尤其是在小的、破碎的活检标本中，可能给诊断带来一定的困难。我们收集2例绝经后女性发生的子宫内膜乳头状黏液性化生，并分析其临床病理特征、KRAS突变的情况，探讨其诊断及鉴别诊断。.

OBJECTIVE: Oxidative stress caused by reactive oxygen species (ROS) plays an important role in the pathogenesis of endometriosis. The gene AT-rich interactive domain 1A (ARID1A), is frequently down regulated and inactivated in endometriosis…