Malgorzata Czystowska

ORCID: 0000-0001-9169-6194 · 5 papers in corpus
article 2024
Determination of Serum Arginase-1 Concentrations and Serum Arginase Activity for the Non-Invasive Diagnosis of Endometriosis
Journal of clinical medicine ·doi:10.3390/jcm13051489

Backgroud: Endometriosis remains a diagnostic challenge, both clinically and economically, affecting 6% to 15% of women of child-bearing potential. We have attempted to determine whether testing serum concentrations and activity of arginase…

dataset 2024
Endometriosis patients cohort - ARG1 ELISA and activity data and clinical data
·doi:10.18150/py1p9x

The data was collected within the NCN project: "Contribution of extracellular vesicles and exosomal arginase to immune dysfunction in endometriosis." The aim of the project is to identify free arginase (ARG) as well as ARG-carrying extracel…

review 2022
Immunosuppressive Extracellular Vesicles as a Linking Factor in the Development of Tumor and Endometriotic Lesions in the Gynecologic Tract
Cells ·doi:10.3390/cells11091483

Both gynecological tumors and endometriosis require for their development a favorable environment, termed in the case of tumors a "pre-metastatic niche" and in case of endometriosis a "pro-endometriotic niche". This is characterized by chro…

2019
Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.
Nature communications ·doi:10.1038/s41467-019-10979-3

Tumor-driven immune suppression is a major barrier to successful immunotherapy in ovarian carcinomas (OvCa). Among various mechanisms responsible for immune suppression, arginase-1 (ARG1)-carrying small extracellular vesicles (EVs) emerge a…

2016
Biological markers of prognosis, response to therapy and outcome in ovarian carcinoma.
Expert review of molecular diagnostics ·doi:10.1080/14737159.2016.1194758

IntroductionOvarian cancer (OvCa) is among the most common types of cancer and is the leading cause of death from gynecological malignancies in western countries. Cancer biomarkers have a potential for improving the management of OvCa patie…