Peña AS

No ORCID on file · 3 papers in corpus · active 2005-2009
2009
TLR9 KO mice, haplotypes and CPG indices in Chlamydia trachomatis infection.
Drugs of today (Barcelona, Spain : 1998) ·doi:10.1358/dot.2009.45.2.1322478

Previous studies have investigated the role of Toll-like receptor (TLR)2 and TLR4 in susceptibility to and severity of Chlamydia trachomatis infections. In this study we employ a unique integrated approach to study the role of the intracell…

2006
Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?
BMC infectious diseases ·doi:10.1186/1471-2334-6-122

BackgroundIn women, Chlamydia (C.) trachomatis upper genital tract infection can cause distal tubal damage and occlusion, increasing the risk of tubal factor subfertility and ectopic pregnancy. Variations, like single nucleotide polymorphis…

2005
The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology.
BMC infectious diseases ·doi:10.1186/1471-2334-5-114

BackgroundThe functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals carrying the T/T genotype also have significantly …