Drugs of today (Barcelona, Spain : 1998)

First-line medical therapies for treating pain associated with endometriosis mainly consist in combined oral contraceptives and progestins. However, some women, having persistence of symptoms, may require further therapeutic options. Among …

Previous studies have investigated the role of Toll-like receptor (TLR)2 and TLR4 in susceptibility to and severity of Chlamydia trachomatis infections. In this study we employ a unique integrated approach to study the role of the intracell…

Laparoscopy currently remains the only effective tool for the diagnosis and evaluation of endometriosis, and in Japan is particularly recommended in patients with concurrent infertility. Diagnosis based on clinical examination alone is asso…

The role of laparoscopy in the diagnosis and medical treatment of endometriosis is changing. Diagnosis based on laparoscopic visualization of endometriotic implants alone is unreliable. However, clinical diagnosis based on noninvasive techn…

Trends in the use of laparoscopy as a diagnostic and treatment tool for endometriosis are changing in the United States and the use of empirical treatment for chronic pelvic pain is on the rise. Although it is regarded as the gold standard …

A comparison of the surgical and medical approach to endometriosis in Europe and the United States reveals similar management strategies for the disease. Although scientific data indicate that laparoscopy alone is not a reliable method of d…

Gonadotropin-releasing hormone (GnRH) agonists are effective in reducing pelvic pain due to endometriosis, but they are associated with a number of hypoestrogenic side effects, such as vasomotor symptoms and loss of bone mineral density. Ad…

Endometriosis is a multifactorial disease affecting up to 15% of women of reproductive age. This condition is characterized by the presence and growth of endometrial cells outside the uterus. Susceptibility to endometriosis depends on compl…

The levonorgestrel intrauterine system is a safe, efficacious, long-term contraceptive device. Additionally, it results in a decrease in the volume of menstrual blood loss in women with normal periods and those with menorrhagia. It may also…