Junken Aoki

ORCID: 0000-0001-9435-1896 · 8 papers in corpus
review 2022
Annual review of pathology ·doi:10.1146/annurev-pathol-050420-025929

Lysophospholipids, exemplified by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are produced by the metabolism and perturbation of biological membranes. Both molecules are established extracellular lipid mediators that sign…

2021
iScience ·doi:10.1016/j.isci.2021.103254

Lysophosphatidic acid (LPA) is a potential regulator of vascular formation derived from blood. In this study, we utilized zebrafish as a model organism to monitor the blood vessel formation in detail. Zebrafish mutant of ATX, an LPA-produci…

article 2021
Biomedicines ·doi:10.3390/biomedicines9111519

Sphingosine 1-phosphate (S1P), an inflammatory mediator, is abundantly contained in red blood cells and platelets. We hypothesized that the S1P concentration in the peritoneal cavity would increase especially during the menstrual phase due …

other 2019
·doi:10.25384/sage.c.4409672

Objects:There is growing evidence that sphingosine 1-phosphate (S1P) is involved in inflammatory diseases. As endometriosis is known as an inflammatory disease, we investigated the role of S1P system in the development of endometriosis.Meth…

other 2019
·doi:10.25384/sage.c.4409672.v1

Objects:There is growing evidence that sphingosine 1-phosphate (S1P) is involved in inflammatory diseases. As endometriosis is known as an inflammatory disease, we investigated the role of S1P system in the development of endometriosis.Meth…

article 2019
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719119828112

ObjectsThere is growing evidence that sphingosine 1-phosphate (S1P) is involved in inflammatory diseases. As endometriosis is known as an inflammatory disease, we investigated the role of S1P system in the development of endometriosis.Metho…

2017
The EMBO journal ·doi:10.15252/embj.201696290

During pregnancy, up-regulation of heparin-binding (HB-) EGF and cyclooxygenase-2 (COX-2) in the uterine epithelium contributes to decidualization, a series of uterine morphological changes required for placental formation and fetal develop…

article 2016
·doi:10.1016/j.jri.2016.10.054