Nikki L Hafezi

No ORCID on file · 3 papers in corpus · active 2019-2025

Study types

  • case-report 1
  • letter 1

Condition tags

  • endometriosis 2
  • infertility 1
2025
Corneal enzymatic digestion resistance in the presence of oestradiol and oestradiol plus selective tissue oestrogenic activity regulators (STEAR).
BMJ open ophthalmology ·doi:10.1136/bmjophth-2025-002208

ObjectiveElevated oestrogen levels and pharmacotherapies targeting oestrogen receptors can reduce corneal biomechanical stability, and altered stromal collagenase activity has been identified as one the possible mechanisms. We wished to det…

case-report 2019
Late-onset progression of keratoconus after therapy with selective tissue estrogenic activity regulator
Journal of cataract and refractive surgery ·doi:10.1016/j.jcrs.2018.08.036

We describe the association of rapid progression of keratoconus in a 49-year-old woman on selective tissue estrogenic activity regulator (STEAR) therapy for endometriosis. Approximately 4 months after initiation of therapy with STEAR therap…

letter 2019
Reply
·doi:10.1016/j.jcrs.2019.04.037

Although more studies are needed to establish the specific role of estrogen in corneal pathophysiology, we agree with Natarajan and Ravindran about the possible association between hormonal variations and corneal alterations, whether topogr…