Marc Possover

This document presents Version 1 (2026) of the ISON Neuropelveological Guidelines for Pelvic Nerve-Sparing Surgery in Gynecology, developed under the auspices of the International Society of Neuropelveology (ISON). The guidelines propose a …

ISON Neuropelveological Guidelines for the Diagnosis and Treatment of Pelvic Radiculopathies/Neuropathies by Vascular Entrapment These guidelines, developed by the International Society of Neuropelveology (ISON), present the first comprehen…

ISON Neuropelveological Guidelines for the Diagnosis and Treatment of Pelvic Radiculopathies/Neuropathies by Vascular Entrapment These guidelines, developed by the International Society of Neuropelveology (ISON), present the first comprehen…

Background : Many women suffer from undiagnosed pelvic pain, potentially due to pelvic neuropathies, but are often treated symptomatically without addressing underlying causes. Pelvic neuropathies can cause severe symptoms, affecting qualit…

Objective The aim of this study was to assess inter-rater reliability for components of the Visual-Numeric Endometriosis Scoring System (VNESS). VNESS is a novel system for describing surgical findings in each compartment of the pelvis in a…

Endometriosis involving the pelvic nerves is perhaps the most challenging scenario faced by the endometriosis surgeon. The diagnosis is difficult as in most cases imaging and other investigations can be unhelpful and the clinician needs to …

A prerequisite for nerve-sparing pelvic surgery is a thorough understanding of the topographic anatomy of the fine and intricate pelvic nerve networks, and their connections to the central nervous system. Insights into the functions of pelv…

Neuropelveology is a new specialty in medicine that has yet to prove itself but the need for it is obvious. This specialty includes the diagnosis and treatment of pathologies and dysfunctions of the pelvic nerves. It encompasses knowledge t…

OBJECTIVE: To report neurologic follow-up of patients after laparoscopic large resection of deep infiltrating endometriosis of the sciatic nerve. DESIGN: Prospective clinical case series. SETTING: Tertiary referral unit specializing in ad…

Chronic pelvic pain (CPP) is a common condition involving multiple, organ-specific medical specialties, each with its own approach to diagnosis and treatment. Management requires knowledge of the interplay between pelvic organ function and …

It is long known that a large portion of the lumbosacral plexus is located intra-abdominally, in the retroperitoneal space. However, most of literature descriptions of lesions on this plexus refer to its extra-abdominal parts whereas its in…

BACKGROUND: Some patients have pelvic, pudendal, or low lumbar pain radiating into the legs that is worse while sitting but differs from pudendal neuralgia. The purpose of this study was to present a new clinical entity of neuropathic pelvi…

STUDY OBJECTIVE: To demonstrate the technique of laparoscopic dissection for identification of sacral nerve roots and pelvic splanchnic nerves. DESIGN: Case report (Canadian Task Force classification III). SETTING: Private practice hospit…

OBJECTIVE: To investigate pathophysiologic mechanisms involved in bladder retention after surgery for rectovaginal deeply infiltrating endometriosis (DIE). DESIGN: Retrospective case study. SETTING: Tertiary referral unit. PATIENT(S): Al…

Die Endometriose ist eine häufige aber wenig bekannte Erkrankung, unter der schätzungsweise 1 von 10 Frauen in ihren fruchtbaren Jahren leidet. Es handelt sich um eine chronische Erkrankung, die durch das Auftreten von Endometriumgewebe aus…

Pudendal nerve entrapment (Alcock canal syndrome) is an uncommon source of chronic pelvic pain, in which the pudendal nerve is entrapped or compressed. Pain is located in the perineal, genital and perianal areas and is worsened by sitting. …

OBJECTIVE: To report our experience with endopelvic causes for sacral radiculopathies and sciatica. DESIGN: Prospective cohort study. SETTING: Tertiary referral advanced laparoscopic gynecology and neuropelveologic unit. PATIENT(S): Two …

STUDY OBJECTIVE: To show the relationship between the neuropeptide-Y pelvic sympathetic nerves and neoangiogenesis in the development of endometriosis DESIGN: Prospective study. SETTING: Academic community teaching hospital. PATIENTS: Fi…

PURPOSE: The feasibility of the laparoscopic transperitoneal approach to the pelvic somatic nerves was determined for the diagnosis and treatment of anogenital pain caused by pudendal and/or sacral nerve root lesions. MATERIALS AND METHODS…

BACKGROUND: The aim of this study is to report on the impact of neuromodulation to the superior hypogastric plexus in patients with bladder atonia secondary to pelvic surgery. METHODS: In 4 consecutive patients with bladder atonia secondar…

OBJECTIVE: To report the impact of the laparoscopic approach to the pelvic nerves in the management of neural pelvic pain in women secondary to pelvic surgery. DESIGN: Clinical prospective study. SETTING: Department of Gynecology and Obst…